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Article
Open AccesseNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity
The roles of nitric oxide (NO) and endothelial NO synthase (eNOS) in the regulation of angiogenesis are well documented. However, the involvement of eNOS in the sprouting of endothelial tip-cells at the vascul...
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Article
Open AccessHIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of...