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  1. No Access

    Chapter

    Molecular Imaging of PD-1 Unveils Unknown Characteristics of PD-1 Itself by Visualizing “PD-1 Microclusters”

    Programmed cell death-1 (PD-1) is one of the most famous coinhibitory receptors that are expressed on effector T cells to regulate their function. The PD-1 ligands, PD-L1 and PD-L2, are expressed by various ce...

    Wataru Nishi, Ei Wakamatsu… in Basic Immunology and Its Clinical Applicat… (2024)

  2. No Access

    Article

    LC–MS/MS-based metabolome analysis detected changes in the metabolic profiles of small and large intestinal adenomatous polyps in Apc Min/+ mice

    The adenomatous polyposis coli (APC) gene is a tumor suppressor gene that is inactivated in the initiation of colorectal neoplasia. Apc Min/+ mice, which ...

    Makoto Suzuki, Shin Nishiumi, Takashi Kobayashi, Takeshi Azuma… in Metabolomics (2016)

  3. No Access

    Article

    Linkage map**, molecular cloning and functional analysis of soybean gene Fg2 encoding flavonol 3-O-glucoside (1 → 6) rhamnosyltransferase

    There are substantial genotypic differences in the levels of flavonol glycosides (FGs) in soybean leaves. The first objective of this study was to identify and locate genes responsible for FG biosynthesis in t...

    Felipe Rojas Rodas, Tito O. Rodriguez, Yoshinori Murai… in Plant Molecular Biology (2014)

  4. No Access

    Article

    Rice-Arabidopsis FOX line screening with FT-NIR-based fingerprinting for GC-TOF/MS-based metabolite profiling

    The full-length cDNA over-expressing (FOX) gene hunting system is useful for genome-wide gain-of-function analysis. The screening of FOX lines requires a high-throughput metabolomic method that can detect a wi...

    Makoto Suzuki, Miyako Kusano, Hideki Takahashi, Yumiko Nakamura… in Metabolomics (2010)

  5. No Access

    Chapter

    Molecular Cloning of a New Aquaporin Superfamily in Mammals

    Currently, aquaporins (AQPs) are divided into two subfamilies: AQP1 group and AQP3 group. AQP1 group is water-selective AQP and has 6 members in mammals: AQPO, AQP1, AQP2, AQP4, AQP5, AQP6. They share similar ...

    Kenichi Ishibashi, Michio Kuwahara… in Molecular Biology and Physiology of Water … (2000)

  6. No Access

    Article

    F-actin network may regulate a Cl− channel in renal proximal tubule cells

    A variety of mechanisms have been proposed for the regulation of ion channel molecules. As integral membrane proteins, ion channels may interact with the cytoskeleton. Regulation of channels by the actin netwo...

    Makoto Suzuki, Keiko Miyazaki, Masato Ikeda… in The Journal of Membrane Biology (1993)

  7. No Access

    Chapter

    Amphoteric Polyvinyl Alcohol Hydrogel and Electrohydrodynamic Control Method for Artificial Muscles

    Since Kuhn and Katchalsky et al.1 first demonstrated artificial muscle in 1950, various mechanochemical materials have been presented.2 From the view point of mechanical engineering, great hopes are set on these ...

    Makoto Suzuki in Polymer Gels (1991)