12 Result(s)
within
Hepatology
Makoto Sunamura
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Article
5th Japanese Association of Hepato-Biliary-Pancreatic Surgery
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Article
How I do it — Necrosectomy in acute pancreatitis. Open drainage with diverting ileostomy for acute necrotizing pancreatitis
Infected pancreatic necrosis which spreads extensively in the retroperitoneal space requires open drainage to prevent the formation of residual abscess. With open drainage and repeated debridement, we often en...
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Article
Strategy for treatment of acute necrotizing pancreatitis: Importance of continuous regional arterial infusion of protease inhibitor and antibiotics in the early phase
A new strategy for the treatment of acute necrotizing pancreatitis (ANP) is reported. In this prospective study, all patients received intensive medical support. Surgery was performed in patients with infected...
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Article
Mucin-producing tumor of the pancreas — surgical treatment
To evaluate appropriate surgical treatment and to predict prognosis for mucin-producing tumors (MPTs) of the pancreas, we conducted a retrospective clinicopathological study in 25 patients with MPT. Eight pati...
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Article
Pancreatic microcirculation in acute pancreatitis
We present a review of the microvascular morphology of the pancreas and microstructure of the pancreatic lobule, and report our experimental results of the investigation of pancreatic microcirculation followi...
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Article
Intraoperative radiotherapy for pancreatic adenocarcinoma
Intraoperative radiotherapy (IORT) is an innovative treatment approach for cancer of the pancreas. The common causes of treatment failure in pancreatic cancer are regional recurrence and distant metastasis. W...
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Chapter and Conference Paper
Cytotoxic Effect of Bone Marrow-Derived Dendritic Cells
Some reports suggest that cancer patients have a better prognosis when dendritic cells (DCs) infiltrate their tumors. Although the role of these DCs is not fully understood, we focused on a potential effector ...
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Chapter and Conference Paper
Controlling Tumor Microenvironment by the Antiangiogenesis Strategy
Angiogenesis occurs when the balance between negative and positive regulators inclines toward the latter, allowing the tumor and metastases to develop. Studies have found that genetic alterations may correlate...
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Article
Cytokine modulation in acute pancreatitis
The clinical manifestations of acute pancreatitis (AP) vary significantly from mild to lethal in form, the severity of the disease being largely determined by the actions of various kinds of inflammatory medi...
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Article
Gene therapy for pancreatic cancer based on genetic characterization of the disease
In order to develop an effective therapeutic intervention for patients with pancreatic cancer, we analyzed the association of loss of heterozygosity (LOH) with the clinicopathological features of the disease....
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Article
Intraductal papillary-mucinous adenocarcinoma in the remnant pancreas after pancreatoduodenectomy for cancer of Vater's papilla associated with intraductal papillary-mucinous adenoma
A 72-year-old woman, who had undergone pylorus-preserving pancreatoduodenectomy 3 years before for cancer of Vater's papilla associated with a branch-type intraductal papillary-mucinous adenoma (IPMA), develop...
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Article
The PMAIP1 Gene on Chromosome 18 is a Candidate Tumor Suppressor Gene in Human Pancreatic Cancer
Frequent loss of heterozygosity on the long arm of chromosome 18 is observed in pancreatic cancer. Previous studies suggested the existence of one or more tumor-suppressor genes other than SMAD4 on chromosome 18....
