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    Article

    S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells

    Pancreatic ductal adenocarcinoma (PDAC) is the 5th most common cause of cancer death in the UK and the 4th in the US. The vast majority of deaths following pancreatic cancer are due to metastatic spread, hence...

    Sayka Barry, Claude Chelala, Kate Lines in Clinical & Experimental Metastasis (2013)

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    Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

    Our previous study indicated that DUSP6/MKP-3/PYST1 could act as a tumor suppressor in human pancreatic cancer. DUSP6 was frequently underexpressed in primary pancreatic cancer tissues by an unknown mechanism....

    Shanhai Xu, Toru Furukawa, Naomi Kanai, Makoto Sunamura in Journal of Human Genetics (2005)

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    Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer

    Angiogenesis is necessary for the continued growth of solid tumors, invasion and metastasis. Several studies clearly showed that heme oxygenase-1 (HO-1) plays an important role in angiogenesis. In this study, ...

    Makoto Sunamura, Dan G. Duda, Maivel H. Ghattas, Lucian Lozonschi in Angiogenesis (2003)