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Article
Open AccessEffects of improved amino acid balance diet on lysine mammary utilization, whole body protein turnover and muscle protein breakdown on lactating sows
The study objective was to test the hypothesis that low crude protein (CP) diet with crystalline amino acids (CAA) supplementation improves Lys utilization efficiency for milk production and reduces protein tu...
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Use of RT-qPCR for Measuring the Expression of the Fecal MicroRNA from the Consumption of Pomegranate Fruit Juice
The ongoing process involves the modification and improvement of the stool test that has been validated for the purpose of diagnostic screening of colon cancer (CC). This particular test focuses on the detecti...
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Article
Open AccessMYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
Neuroblastoma (NB) is a childhood cancer arising from sympatho-adrenal neural crest cells. MYCN amplification is found in half of high-risk NB patients; however, no available therapies directly target MYCN. Using...
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Article
Open AccessElucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration
Human Milk Oligosaccharides (HMOs) are abundant carbohydrates fundamental to infant health and development. Although these oligosaccharides were discovered more than half a century ago, their biosynthesis in t...
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Article
Open AccessCorrecting for sparsity and interdependence in glycomics by accounting for glycan biosynthesis
Glycans are fundamental cellular building blocks, involved in many organismal functions. Advances in glycomics are elucidating the essential roles of glycans. Still, it remains challenging to properly analyze ...
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Article
Open AccessRestoration of the molecular clock is tumor suppressive in neuroblastoma
MYCN activation is a hallmark of advanced neuroblastoma (NB) and a known master regulator of metabolic reprogramming, favoring NB adaptation to its microenvironment. We found that the expression of the main re...
