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  1. Article

    Open Access

    Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors

    Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While map** these relationships between TFs is important for understanding th...

    Anna Berenson, Ryan Lane, Luis F. Soto-Ugaldi, Mahir Patel in Nature Communications (2023)

  2. Article

    Open Access

    Animal Pose Tracking: 3D Multimodal Dataset and Token-based Pose Optimization

    Accurate tracking of the 3D pose of animals from video recordings is critical for many behavioral studies, yet there is a dearth of publicly available datasets that the computer vision community could use for ...

    Mahir Patel, Yiwen Gu, Lucas C. Carstensen in International Journal of Computer Vision (2023)

  3. Article

    Open Access

    Emerging Therapies for the Treatment of Psoriasis

    Psoriasis is an immune-mediated disease that affects 1%–2% of the European and North American population. While topical agents such as corticosteroids and vitamin D derivatives are prescribed for mild disease,...

    Mahir Patel, Antoinette Day, Richard B. Warren, Alan Menter in Dermatology and Therapy (2012)

  4. No Access

    Article

    Obesity Is Associated with an Increased Prevalence of Advanced Adenomatous Colon Polyps in a Male Veteran Population

    Obesity has been associated with an increased risk for colonic adenomatous polyps (APs) and colorectal cancers, but the influence of obesity on the development of advanced APs is not clear. The purpose of this...

    Ali Siddiqui, Helene N. Pena Sahdala, Hector E. Nazario in Digestive Diseases and Sciences (2009)

  5. No Access

    Article

    For Patients with Colorectal Cancer, the Long-Term Use of Statins Is Associated with Better Clinical Outcomes

    Statins have been found to suppress tumor cell growth and to limit the ability of tumor cells to metastasize in studies involving cell lines and animals. To explore how the long-term use of statins influences ...

    Ali A. Siddiqui, Hector Nazario, Amar Mahgoub in Digestive Diseases and Sciences (2009)