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Article
Open AccessPaired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors
Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While map** these relationships between TFs is important for understanding th...
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Article
Open AccessAnimal Pose Tracking: 3D Multimodal Dataset and Token-based Pose Optimization
Accurate tracking of the 3D pose of animals from video recordings is critical for many behavioral studies, yet there is a dearth of publicly available datasets that the computer vision community could use for ...
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Article
Open AccessEmerging Therapies for the Treatment of Psoriasis
Psoriasis is an immune-mediated disease that affects 1%–2% of the European and North American population. While topical agents such as corticosteroids and vitamin D derivatives are prescribed for mild disease,...
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Article
Obesity Is Associated with an Increased Prevalence of Advanced Adenomatous Colon Polyps in a Male Veteran Population
Obesity has been associated with an increased risk for colonic adenomatous polyps (APs) and colorectal cancers, but the influence of obesity on the development of advanced APs is not clear. The purpose of this...
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Article
For Patients with Colorectal Cancer, the Long-Term Use of Statins Is Associated with Better Clinical Outcomes
Statins have been found to suppress tumor cell growth and to limit the ability of tumor cells to metastasize in studies involving cell lines and animals. To explore how the long-term use of statins influences ...