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  1. Article

    Open Access

    Genome-wide association studies for methane emission and ruminal volatile fatty acids using Holstein cattle sequence data

    Methane emission by ruminants has contributed considerably to the global warming and understanding the genomic architecture of methane production may help livestock producers to reduce the methane emission fro...

    Ali Jalil Sarghale, Mohammad Moradi Shahrebabak, Hossein Moradi Shahrebabak in BMC Genetics (2020)

  2. Article

    Open Access

    Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle

    Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for inclusion in modern breeding and selection programs. Usin...

    Christopher M. Seabury, David L. Oldeschulte, Mahdi Saatchi in BMC Genomics (2017)

  3. Article

    Open Access

    Accuracy of prediction of simulated polygenic phenotypes and their underlying quantitative trait loci genotypes using real or imputed whole-genome markers in cattle

    More accurate genomic predictions are expected when the effects of QTL (quantitative trait loci) are predicted from markers in close physical proximity to the QTL. The objective of this study was to quantify t...

    Saeed Hassani, Mahdi Saatchi, Rohan L. Fernando in Genetics Selection Evolution (2015)

  4. Article

    Open Access

    QTLs associated with dry matter intake, metabolic mid-test weight, growth and feed efficiency have little overlap across 4 beef cattle studies

    The identification of genetic markers associated with complex traits that are expensive to record such as feed intake or feed efficiency would allow these traits to be included in selection programs. To identi...

    Mahdi Saatchi, Jonathan E Beever, Jared E Decker, Dan B Faulkner in BMC Genomics (2014)

  5. Article

    Open Access

    Large-effect pleiotropic or closely linked QTL segregate within and across ten US cattle breeds

    The availability of high-density SNP assays including the BovineSNP50 (50 K) enables the identification of novel quantitative trait loci (QTL) and improvement of the resolution of the locations of previously m...

    Mahdi Saatchi, Robert D Schnabel, Jeremy F Taylor, Dorian J Garrick in BMC Genomics (2014)

  6. Article

    Open Access

    Recombination locations and rates in beef cattle assessed from parent-offspring pairs

    Recombination events tend to occur in hotspots and vary in number among individuals. The presence of recombination influences the accuracy of haplotype phasing and the imputation of missing genotypes. Genes th...

    Zi-Qing Weng, Mahdi Saatchi, Robert D Schnabel in Genetics Selection Evolution (2014)

  7. Article

    Open Access

    Genome-wide association and prediction of direct genomic breeding values for composition of fatty acids in Angus beef cattlea

    As consumers continue to request food products that have health advantages, it will be important for the livestock industry to supply a product that meet these demands. One such nutrient is fatty acids, which ...

    Mahdi Saatchi, Dorian J Garrick, Richard G Tait Jr, Mary S Mayes in BMC Genomics (2013)

  8. Article

    Open Access

    Comparison of molecular breeding values based on within- and across-breed training in beef cattle

    Although the efficacy of genomic predictors based on within-breed training looks promising, it is necessary to develop and evaluate across-breed predictors for the technology to be fully applied in the beef in...

    Stephen D Kachman, Matthew L Spangler, Gary L Bennett in Genetics Selection Evolution (2013)

  9. Article

    Open Access

    Accuracy of direct genomic breeding values for nationally evaluated traits in US Limousin and Simmental beef cattle

    In national evaluations, direct genomic breeding values can be considered as correlated traits to those for which phenotypes are available for traditional estimation of breeding values. For this purpose, estim...

    Mahdi Saatchi, Robert D Schnabel, Megan M Rolf in Genetics Selection Evolution (2012)

  10. Article

    Open Access

    Accuracies of genomic breeding values in American Angus beef cattle using K-means clustering for cross-validation

    Genomic selection is a recently developed technology that is beginning to revolutionize animal breeding. The objective of this study was to estimate marker effects to derive prediction equations for direct gen...

    Mahdi Saatchi, Mathew C McClure, Stephanie D McKay in Genetics Selection Evolution (2011)