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  1. Article

    Open Access

    Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

    Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors.

    **ao**g Chu, Martin Jaeger, Joep Beumer, Olivier B. Bakker… in Genome Biology (2021)

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    Article

    Fructose stimulated de novo lipogenesis is promoted by inflammation

    Benign hepatosteatosis, affected by lipid uptake, de novo lipogenesis and fatty acid (FA) oxidation, progresses to non-alcoholic steatohepatitis (NASH) on stress and inflammation. A key macronutrient proposed ...

    Jelena Todoric, Giuseppe Di Caro, Saskia Reibe, Darren C. Henstridge… in Nature Metabolism (2020)