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    Article

    Ezurpimtrostat, A Palmitoyl-Protein Thioesterase-1 Inhibitor, Combined with PD-1 Inhibition Provides CD8+ Lymphocyte Repopulation in Hepatocellular Carcinoma

    Palmitoyl-protein thioesterase-1 (PPT1) is a clinical stage druggable target for inhibiting autophagy in cancer.

    Eloïne Bestion, Madani Rachid, Annemilaï Tijeras-Raballand, Gael Roth… in Targeted Oncology (2024)

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    Article

    Phase I study of veliparib in combination with gemcitabine

    Veliparib (ABT-888) is an oral PARP inhibitor expected to increase gemcitabine activity. This phase I determined the maximal tolerable dose (MTD), dose-limiting toxicities (DLT), antitumor activity, pharmacoki...

    Ronald Stoller, John C. Schmitz, Fei Ding… in Cancer Chemotherapy and Pharmacology (2017)