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Article
Open AccessStaphylococcal phages and pathogenicity islands drive plasmid evolution
Conjugation has classically been considered the main mechanism driving plasmid transfer in nature. Yet bacteria frequently carry so-called non-transmissible plasmids, raising questions about how these plasmids...
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Article
Open AccessNew insights on Pseudoalteromonas haloplanktis TAC125 genome organization and benchmarks of genome assembly applications using next and third generation sequencing technologies
Pseudoalteromonas haloplanktis TAC125 is among the most commonly studied bacteria adapted to cold environments. Aside from its ecological relevance, P. haloplanktis has a potential use for biotechnological applic...
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Article
Open AccessMistranslation can enhance fitness through purging of deleterious mutations
Phenotypic mutations are amino acid changes caused by mistranslation. How phenotypic mutations affect the adaptive evolution of new protein functions is unknown. Here we evolve the antibiotic resistance protei...
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Article
Open AccessInteractions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa
Horizontal gene transfer (HGT) plays a key role in bacterial evolution, especially with respect to antibiotic resistance. Fitness costs associated with mobile genetic elements (MGEs) are thought to constrain H...
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Article
Open AccessEmergence of novel domains in proteins
Proteins are composed of a combination of discrete, well-defined, sequence domains, associated with specific functions that have arisen at different times during evolutionary history. The emergence of novel do...
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Chapter
Accelerated Evolution of Genes of Recent Origin
The gene content of any genome is a rich mosaic of genes that have originated at different times during evolution. Among the most interesting properties related to gene age is the fact that younger genes tend ...
