9 Result(s)
-
Article
Predicting pharmacokinetic properties of potential anti-cancer agents using micellar thin-layer chromatography
The thin-layer chromatography technique with a micellar mobile phase was used to predict the pharmacokinetic properties of newly synthesized azaisocytosine-containing congeners that are considered as potential...
-
Article
A Comparative Study of the Lipophilicity of 1,2,4-Triazoles by Reversed-Phase and Micellar TLC and OPLC
Lipophilicities of 21 newly synthesized 1,2,4-triazoles, compounds of potential importance as fungicides, have been determined by micellar and reversed-phase planar chromatography. Different stationary and mob...
-
Article
Chromatographic Evaluation of the Lipophilicity of N-Phenyltrichloroacetamide Derivatives using Micellar TLC and OPLC
Micellar liquid chromatography (MLC) has been used to study the lipophilicity of eight newly synthesized N-phenyltrichloroacetamide derivatives. Because the lipophilicity of a substance determines its retention a...
-
Article
Crucial Role of Formaldehyde and its Reaction Products in the Antiproliferative Activity of Some Potential Pesticides
A group of thirteen newly synthesized potential herbicides, N-aryl-trichloroacetamides or 2-(chlorophenoxy)acyl derivatives, have been initially investigated by reversed phase (RP) TLC. The lipophilicity of the s...
-
Article
Use of Thin-Layer and Over-Pressured-Layer Chromatography to Study the Hydrophobicity of Homologous s-Triazines
Retention factors in pure water, log kw, determined by linear extrapolation and by a numerical method based on Ościk’s equation, and calculated values of log P have been compared as hydrophobicity indices for nin...
-
Article
Comparison of Different Properties — log P, logkw, and ϕ0 — as Descriptors of the Hydrophobicity of Some Fungicides
Log P, log kw, and ϕ0, are proposed and compared as descriptors of the hydrophobicity of twenty-two dihydroxythiobenzanilides — organic substances with antifungal properties. The log P values were calculated usin...
-
Article
Thin-Layer and Overpressured-Layer Chromatography for Evaluation of the Hydrophobicity of s-Triazine Derivatives
The retention factor in pure water, log kw, is proposed as a measure of the hydrophobicity of s-triazine derivatives. In these studies two reversed-phase techniques, thin-layer chromatography (TLC) and overpressu...
-
Article
Planar Chromatography in Studies of the Hydrophobic Properties of Some New Herbicides
Reversed-phase planar chromatography has been used to study the hydrophobic properties of sixteen new herbicides. Solute retention factors in pure water, log kw, were determined by linear extrapolation and by the...
-
Article
The Effect of Stationary Phase Type and Mobile Phase pH on the Separation of Some Catecholamines
The catecholamines are very important in the control and regulation of a variety of functions acting as neurotransmitters in both central and peripheral nervous systems. Determination of the levels of catechol...
