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  1. Article

    Open Access

    DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma

    Glaucoma is the leading cause of irreversible blindness and is characterized by slow and progressive degeneration of the optic nerve head axons and retinal ganglion cell (RGC), leading to loss of visual functi...

    K-Y Kim, G A Perkins, M S Shim, E Bushong, N Alcasid, S Ju… in Cell Death & Disease (2015)

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  2. Article

    Open Access

    Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury

    Cyclosporin A (CsA) inhibits the opening of the mitochondrial permeability transition pore (MPTP) by interacting with cyclophilin D (CypD) and ameliorates neuronal cell death in the central nervous system agai...

    S Y Kim, M S Shim, K-Y Kim, R N Weinreb, L A Wheeler, W-K Ju in Cell Death & Disease (2014)

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  3. Article

    Open Access

    Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes

    Oxidative stress contributes to dysfunction of glial cells in the optic nerve head (ONH). However, the biological basis of the precise functional role of mitochondria in this dysfunction is not fully understoo...

    Y H Noh, K-Y Kim, M S Shim, S-H Choi, S Choi, M H Ellisman… in Cell Death & Disease (2013)

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  4. No Access

    Article

    Texture Evolution in Mg-Zn-Ca Alloy Sheets

    Ca was added to Mg-1Zn and Mg-6Zn alloys to modify their texture, and the origin of texture modification by Ca addition has been investigated. It shows that Mg-1Zn-1Ca (ZX11) and Mg-6Zn-1Ca (ZX61) alloy sheets...

    D.-W. Kim, B.-C. Suh, M.-S. Shim, J. H. Bae… in Metallurgical and Materials Transactions A (2013)

  5. No Access

    Article

    Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor

    dSelK (G-rich), a homolog of human and mouse SelK, is one of three selenoproteins in Drosophila melanogaster. It is the only trans-membrane selenoprotein in D. melanogaster integrated into both the endoplasmic re...

    S. B. Ben, Q. Y. Wang, L. **a, J. Z. **a, J. Cui, J. Wang, F. Yang… in Biochemistry (Moscow) (2011)