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Article
Myositis als postakute Folge einer COVID-19-Erkrankung?
Es wird über eine an COVID-19 erkrankte Patientin mit Verdacht auf eine Myositis als Folge einer SARS-CoV-2-Infektion berichtet. Initial führte wenig Information über die Krankengeschichte zur erschwerten hist...
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Article
Open AccessBehandlung retroperitonealer Sarkome in Deutschland
Retroperitoneale Sarkome sind seltene bösartige Tumore. In Deutschland existieren keine zentralisierte Behandlung und keine nationale Behandlungsleitlinie für retroperitoneale Sarkome. Ziel dieser Studie ist d...
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Article
Open AccessVEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors
The inadequate transport of drugs into the tumor tissue caused by its abnormal vasculature is a major obstacle to the treatment of cancer. Anti-vascular endothelial growth factor (anti-VEGF) drugs can cause ph...
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Article
Open AccessExpression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
There is evidence that tumour–stroma interactions have a major role in the neoplastic progression of pancreatic ductal adenocarcinoma (PDAC). Tumour budding is thought to reflect the process of epithelial–mese...
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Article
Open AccessIncreased doxorubicin uptake and toxicity in multicellular tumour spheroids treated with DC electrical fields
Electrochemotherapy (ECT) is a new approach to the treatment of tumours. In the present study, multicellular prostate tumour spheroids were treated with non-lethal direct current (DC) electrical fields, and up...
