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  1. Article

    Open Access

    HLA-class I markers and multiple sclerosis susceptibility in the Italian population

    Previous studies reported an association with multiple sclerosis (MS) of distinct HLA-class I markers, namely HLA-A*02, HLA-Cw*05 and MOG-142L. In this work, we tested the association with MS of A*02 and Cw*05 in...

    L Bergamaschi, M A Leone, M E Fasano, F R Guerini, D Ferrante… in Genes & Immunity (2010)

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  2. No Access

    Article

    Variations of the perforin gene in patients with multiple sclerosis

    Perforin is involved in cell-mediated cytotoxicity and mutations of its gene (PRF1) cause familial hemophagocytic lymphohistiocytosis (FLH2). PRF1 sequencing in 190 patients with multiple sclerosis and 268 contro...

    G Cappellano, E Orilieri, C Comi, A Chiocchetti, S Bocca, E Boggio… in Genes & Immunity (2008)

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    Article

    A sequence variation in the MOG gene is involved in multiple sclerosis susceptibility in Italy

    Several studies suggest that the histocompatibility complex (HLA) class I region harbours genes modulating multiple sclerosis (MS) susceptibility independently from the effect of class II alleles. A candidate ...

    S D'Alfonso, E Bolognesi, F R Guerini, N Barizzone, S Bocca, D Ferrante… in Genes & Immunity (2008)