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Article
A retrospective study of myocardial infarction occurring in elderly patients in a coronary care unit
Myocardial infarction is a major cause of morbidity and mortality particularly in the elderly. Coronary Care Unit monitoring has resulted in the improvement in prognosis in all age groups. In this study, the c...
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Article
ICI 141,292 (epanolol) —pharmacokinetics after single and repeated oral administration in the elderly with moderate renal impairment
The pharmacokinetics of ICI 141,292 (epanolol) were studied over 3 days after a single oral 200 mg dose and then over 24 h after 12 consecutive daily oral 200 mg doses in 16 elderly subjects (aged 65 to 94 yea...
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Article
Pharmacokinetics of oral acetyl-L-carnitine in renal impairment
Acetyl-L-carnitine 1.5 g and 3.0 g was administered as three divided doses on each of two occasions to 24 people with varying renal failure (creatinine clearance 127 – 8 ml·min−1). Plasma and urinary concentratio...
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Article
Irish cardiac society
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Article
Royal academy of medicine in Ireland section of medicine
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Article
Serum theophylline — A mandatory measurement in the control of therapy?
Sustained release (SR) oral theo-phylline preparations have been used in the long term treatment of obstructive airways disease (OAD) in increasing numbers of patients in recent years. The maximum bronchodilat...
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Article
Irish cardiac society
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Article
β-Adrenoceptor Blocking Drugs and Renal Blood Flow with Special Reference to the Elderly
Adrenergic receptors in the kidney mediate changes in renal blood flow. α-Adrenoceptor stimulation results in vasoconstriction while stimulation of β1-adrenoceptors has a similar effect mediated through the renin...