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Article
Open AccessMultidomain Intervention Trial for Preventing Cognitive Decline among Older Adults with Type 2 Diabetes: J-MIND-Diabetes
No multidomain intervention trials have been designed for the prevention of cognitive decline in older adults with type 2 diabetes.
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Chapter
Targeted Up-Conditioning of Contralesional Corticospinal Pathways Promotes Motor Recovery in Poststroke Patients with Severe Chronic Hemiplegia
Impairment of shoulder elevation in poststroke hemiplegia is a debilitating condition with no evidence-based, accessible treatment. This study evaluated the safety and efficacy of direct brain control of adva...
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Article
Open AccessHigh-dose chemotherapy followed by autologous stem cell transplantation for relapsed/refractory primary mediastinal large B-cell lymphoma
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Article
Electrically driven single-photon source at room temperature in diamond
Single-photon sources that provide non-classical light states on demand have a broad range of applications in quantum communication, quantum computing and metrology1. Single-photon emission has been demonstrated ...
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Article
Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats
Varying degrees of metabolic abnormalities mediated by chronic inflammation are implicated in the chronic glomerular injuries associated with obesity. Interleukin (IL)-10, a pleiotropic cytokine, exerts anti-i...
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Article
Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice
Metformin, the major target of which is liver, is commonly used to treat type 2 diabetes. Although metformin activates AMP-activated protein kinase (AMPK) in hepatocytes, the mechanism of activation is still n...
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Article
Electron Emission from Diamond (111) p +-i-n+ Junction Diode
We successfully observed electron emission from hydrogenated diamond (111) p +-i-n+ junction diodes. Here, p +- and n +-layers mean that the boron and phosphorous impurity concentrations in these layers are aroun...
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Chapter and Conference Paper
β-Ray angular distribution from purely nuclear spin aligned 20F
The alignment correlation term in the β-ray angular distribution from purely nuclear spin aligned 20F has been measured to test the G-parity conservation law which is one of the fundamental symmetries in the weak...
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Chapter and Conference Paper
Hyperfine interactions of half-metallic diluted antiferromagnetic semiconductors
Half-metallic diluted antiferromagnetic semiconductors (HM-AF-DMSs) are magnetic materials that are half-metallic and yet do not exhibit magnetization. The remarkable features of these materials and the possib...
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Chapter and Conference Paper
Electric field gradient at 12N implanted into ZnO
The nuclear quadrupole interaction of short-lived β-emitter 12N(I=1, T 1/2=11 ms) implanted into a ZnO single crystal has been studied by means of the β-NMR method. We have observed a quadrup...
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Chapter and Conference Paper
Spin-lattice relaxation of 25Al and 28P in Pt
The spin-lattice relaxation times T 1 for short-lived β emitters 25Al(I=5/2, T 1/2=7.2 s) and 28P(I=3, T 1/2=270 ms) in Pt were measured by means of ...
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Chapter and Conference Paper
Nuclear spin manipulation in interfaces of diluted magnetic semiconductors
Nuclear spin manipulation using an interface of diluted magnetic semiconductors (DMSs) is proposed. On the basis of the first-principles electronic structure calculation, we show that the hyperfine fields at a...
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Chapter and Conference Paper
Temperature dependence of Knight shifts for 12B in Pt
The Knight shift of a short lived β-emitting nucleus 12B (I=1, T 1/2=20 ms) implanted into Pt has been measured as a function of temperature (140–600 K) by means of the β-NMR method. The rela...
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Article
β-Ray angular distribution from purely nuclear spin aligned 20F
The alignment correlation term in the β-ray angular distribution from purely nuclear spin aligned 20F has been measured to test the G-parity conservation law which is one of the fundamental symmetries in the weak...
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Article
Spin-lattice relaxation of 25Al and 28P in Pt
The spin-lattice relaxation times T 1 for short-lived β emitters 25Al(I = 5/2, T 1/2 = 7.2 s) and 28P(I = 3, T 1/2 = 270 ms) in Pt were meas...
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Article
Electric field gradient at 12 N implanted into ZnO
The nuclear quadrupole interaction of short-lived β-emitter 12N(I = 1, T 1/2 = 11 ms) implanted into a ZnO single crystal has been studied by means of the β-NMR method. We have observed a ...
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Article
Temperature dependence of Knight shifts for 12 B in Pt
The Knight shift of a short lived β-emitting nucleus 12B (I = 1, T 1/2 = 20 ms) implanted into Pt has been measured as a function of temperature (140−600 K) by means of the β-NMR method. T...
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Article
Open AccessAdenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts
Hypoxia is closely associated with the radioresistance of tumours; therefore, targeting hypoxic areas is very important for cancer therapy. The aim of this study is to establish such a targeting strategy by ap...
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Article
High-dose chemotherapy and autologous peripheral blood stem cell transfusion for adult and adolescent patients with small round cell sarcomas
The treatment of small-round-cell tumors (SRCT) in adult patients remains a challenge to clinicians. In the present study, we analyzed the feasibility and efficacy of high-dose chemotherapy (HDCT) followed by ...
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Article
Nuclear spin manipulation in interfaces of diluted magnetic semiconductors
Nuclear spin manipulation using an interface of diluted magnetic semiconductors (DMSs) is proposed. On the basis of the first-principles electronic structure calculation, we show that the hyperfine fields at a...