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Open AccessCorrection: SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior
This article was originally published under standard licence, but has now been made available under a [CC BY 4.0] license. The PDF and HTML versions of the paper have been modified accordingly.
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Article
Open AccessSSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior
Antidepressants that block the serotonin transporter, (Slc6a4/SERT), selective serotonin reuptake inhibitors (SSRIs) improve mood in adults but have paradoxical long-term effects when administered during perin...
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Article
Open AccessNicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells’ activity
Epidemiological studies report strong association between mood disorders and tobacco addiction. This high comorbidity requires adequate treatment but the underlying mechanisms are unknown. We demonstrate that ...
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Article
GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper
Endoplasmic reticulum (ER) release and cell-surface export of many G protein-coupled receptors (GPCRs) are tightly regulated. For gamma-aminobutyric acid (GABA)B receptors of GABA, the major mammalian inhibitory ...
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Article
The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens
Tonically active cholinergic interneurons (TANs) from the nucleus accumbens (NAc) are centrally involved in reward behavior. TANs express a vesicular glutamate transporter referred to as VGLUT3 and thus use bo...
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Article
Mechanisms of synaptic depression triggered by metabotropic glutamate receptors
Glutamate, by activation of metabotropic receptors (mGluRs), can lead to a reduction of synaptic efficacy at many synapses. These forms of synaptic plasticity are referred to as long-term depression (mGluR-LTD...
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Article
The expression pattern of four odorant-binding proteins in male and female silk moths, Bombyx mori
Four recombinant odorant-binding proteins of Bombyx mori, pheromone-binding protein (PBP), general odorant-binding protein 1 (GOBP1), general odorant-binding protein 2 (GOBP2) and antennal binding protein X (ABPX...
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Article
Nuclease activity in human metaphase chromosomes substituted with 5′-bromodeoxyuridine
Human metaphase chromosomes, substituted with 5′-bromodeoxyuridine (BrdUrd) for one, two or three rounds of replication, were briefly pretreated with ultraviolet light (UV), in the presence of 33258 Hoechst, a...
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Article
A case of D13 ring chromosome
A case of D ring chromosome identified with trypsin banding as a 13 with loss of the bands p12 and q34 is reported. The clinical features characteristically associated with the loss of these specific segments ...
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Article
A further case of a 22;22 Robertsonian translocation associated with recurrent abortions
A case of 22;22 Robertsonian translocation, identified in the husband of a woman who had five early abortions, is reported.
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Article
The nuclear content of DNA in three different strains ofArtemia salina leach (Phyllopoda, Branchiopodidae)
DNS-Messungen an Interphasekernen vonArtemia salina parthenogenetica 2n undArtemia salina anfigonica zeigen ein Mengenverhältnis von 1.2∶1, während zwischenArtemia salina parthenogenetica 4n undArtemia salina anf...
