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Article
Open AccessCharacterizing the features and course of psychiatric symptoms in children and adolescents with autoimmune encephalitis
Autoimmune encephalitis (AE) can present like a psychiatric disorder. We aimed to illustrate the psychiatric manifestations, course and management of AE in a paediatric cohort. Neuropsychiatric symptoms, inves...
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Article
Treatment of MOG antibody associated disorders: results of an international survey
While monophasic and relapsing forms of myelin oligodendrocyte glycoprotein antibody associated disorders (MOGAD) are increasingly diagnosed world-wide, consensus on management is yet to be developed.
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Article
Correction: DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer
The final sentence of the Acknowledgements should be as follows: This work was supported by grants from Instituto de Salud Carlos III (BA15/00092), Spanish Ministry of Economy and Competitiveness/EU-ERDF (SAF2...
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Article
Erratum: DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer
Correction to: Oncogene (2017) 36, 4802–4809; doi:10.1038/onc.2017.21; published online 13 March 2017 Since the publication of the above article the authors have noticed that the siRNA DUB3 oligonucleotide seq...
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Article
DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer
Correct control of DNA replication is crucial to maintain genomic stability in dividing cells. Inappropriate re-licensing of replicated origins is associated with chromosomal instability (CIN), a hallmark of c...
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Article
Atypical and anaplastic meningioma: outcomes in a population based study
Atypical and anaplastic meningiomas (AAM) are aggressive tumors. This study is aimed at examining associations between patient and tumor-related factors and tumor-related death in patients with AAM. We conduct...
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Article
Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow
Degeneration of normal hematopoietic cells is a shared feature of malignant diseases in the hematopoietic system. Previous studies have shown the exhaustion of hematopoietic progenitor cells (HPCs) in leukemic...
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Article
Topic: Inguinal Hernia — Unsolved problem in the daily practice
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Article
Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells
Precursor B-lineage acute lymphoblastic leukemia (pre-B ALL) affects hematopoietic development and therefore is associated with immune deficiencies that can be further exacerbated by chemotherapy. It is unclea...
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Article
Galectin-3 in pre-B acute lymphoblastic leukemia
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Article
“Self pop-out”: agency enhances self-recognition in visual search
In real-life situations, we are often required to recognize our own movements among movements originating from other people. In social situations, these movements are often correlated (for example, when dancin...
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Article
Treatment of acute lymphoblastic leukemia with an rGel/BLyS fusion toxin
Acute lymphoblastic leukemia (ALL) is the most common malignancy affecting children and a major cause of mortality from hematopoietic malignancies in adults. A substantial number of patients become drug resist...
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Article
Open AccessPediatric T- and NK-cell lymphomas: new biologic insights and treatment strategies
T- and natural killer (NK)-cell lymphomas are challenging childhood neoplasms. These cancers have varying presentations, vast molecular heterogeneity, and several are quite unusual in the West, creating diagno...
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Article
Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist
The bone marrow (BM) stromal niche can protect acute lymphoblastic leukemia (ALL) cells against the cytotoxicity of chemotherapeutic agents and is a possible source of relapse. The stromal-derived factor-1 (SD...
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Article
Day case laparoscopic herniorraphy
The aim of this study was to evaluate day case laparoscopic herniorraphy (LH) and to ascertain the impact of trainee surgeons on its performance.
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Chapter
Komen er bij verhitten van braadzakken schadelijke stoffen vrij?
Het gebruik van plastic materialen voor verpakking van voedingsmiddelen is de afgelopen jaren sterk toegenomen. Omdat interactie tussen levensmiddel en plastic verpakking mogelijk is, wordt hiernaar regelmatig...
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Chapter
Zijn er risico’s voor het gebruik van zoetstoffen met als ingrediënten maltodextrine en aspartaam?
Maltodextrine is een koolhydraat, behorend tot de disacchariden. Deze stof smaakt veel minder zoet dan gewone suiker en kan ook niet worden beschouwd als zoetstof. Meestal wordt hij in de levensmiddelenindustr...
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Chapter
Is de zogenaamde Diet-patch een gevaarlijk hulpmiddel bij vermagering?
Onder de merknaam ‘Diet-Patch®’ is een pleister te koop waarmee in 4 weken tijd 15 à 45 kilo gewicht zou kunnen worden verloren. De pleister bevat een ‘reeks natuurlijke elementen die de vetstofwisseling stimu...
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Chapter
Kunnen de vegetarische producten ‘schimmeleiwit’ en ‘Tivall’ de vleesbehoefte volledig dekken?
De markt voor vleesvervangers groeit met 15% per jaar. Ongeveer 10% van de consumenten eet regelmatig vleesloos; 3% is volledig vegetariër. De ‘gekkekoeienziekte’ en de varkenspest hebben het imago van vlees f...
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Chapter
Kan het eten van rundvlees of soep trekken van mergpijp leiden tot BSE?
De gekkekoeienziekte (BSE = bovine spongiforme encefalopathie) is een veeziekte, waarvan (nog) niet is aangetoond dat mensen deze kunnen krijgen door het eten van besmet vlees. Op een enkele uitzondering na he...
