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Article
Open AccessArgon blocks the expression of locomotor sensitization to amphetamine through antagonism at the vesicular monoamine transporter-2 and mu-opioid receptor in the nucleus accumbens
We investigated the effects of the noble gas argon on the expression of locomotor sensitization to amphetamine and amphetamine-induced changes in dopamine release and mu-opioid neurotransmission in the nucleus...
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Article
Selective cytotoxic lesions of the retrohippocampal region produce a mild deficit in social recognition memory
Although a number of studies have implicated the hippocampal formation in social recognition memory in the rat, a recent study in this laboratory has demonstrated that selective cytotoxic lesions, confined to...
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Article
The role of the entorhinal cortex in two forms of spatial learning and memory
It is generally acknowledged that the rodent hippocampus plays an important role in spatial learning and memory. The importance of the entorhinal cortex (ERC), an area that is closely interconnected anatomica...
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Article
Contextual fear conditioning is disrupted by lesions of the subcortical, but not entorhinal, connections to the hippocampus
Recent studies have questioned the importance of the entorhinal cortex (ERC) for normal hippocampal function. For example, fibre-sparing ERC lesions have been found to have no effect on spatial learning in th...
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Article
Cytotoxic lesions of the hippocampus increase social investigation but do not impair social-recognition memory
A number of studies have implicated the hippocampal formation in social-recognition memory in the rat. The present study addressed this issue directly by assessing the effects of cytotoxic lesions confined to...
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Article
Twitching and quivering of the tentacles during snail olfactory orientation
In Helix aspersa the posterior tentacles house a sensitive olfactory organ. We studied two types of tentacular movements, twitch and quiver. A twitch is a brief retraction (mean duration, 4.1 s); a quiver is a r...
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Article
CCK-A and CCK-B selective receptor agonists and antagonists modulate olfactory recognition in male rats
Modulation of learning and memory is one of the physiological roles that the neuropeptide cholecystokinin (CCK-8) may play. We have used a behavioural model of olfactory recognition among rats to test this hyp...
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Chapter and Conference Paper
Chemical Structure, Pharmacodynamic Profile and Pharmacokinetics of SMS 201–995 (Sandostatin®)
Natural somatostatin (SRIF) is a tetra-decapeptide with a multiplicity of inhibiting actions on the secretion of a variety of hormones. In vivo, the compound has a biological half-life of only two to three minute...