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Ca2+ channels, Ca2+ sparks, and regulation of arterial smooth muscle function
In cardiac, skeletal, and arterial muscle, transient, spatially localized elevations in [Ca2+]i, termed “Ca2+ sparks”, have been observed using confocal laser scanning microscopy. Ca2+ sparks are thought to repr...
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Aminopeptidase N-Mediated Signal Transduction and Inhibition of Proliferation of Human Myeloid Cells
Cell surface peptidases are involved in degradative processes of various peptides, in cell-cell communcation, in lymphocyte activation and in cell growth1,2,3,4. Aminopeptidase N (APN, CD 13), a ubiquitously occu...