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  1. No Access

    Article

    On the coexistence of convergence and divergence phenomena for integral averages and an application to the Fourier–Haar series

    Let \(C,D\subset \mathbb{N}\) C , D ...

    M. Hirayama, D. Karagulyan in Analysis Mathematica (2024)

  2. No Access

    Article

    Spontaneous topological Hall effect induced by non-coplanar antiferromagnetic order in intercalated van der Waals materials

    In ferromagnets, an electric current generally induces a transverse Hall voltage in proportion to the internal magnetization. This effect is frequently used for the electrical readout of the spin-↑ and spin-↓ ...

    H. Takagi, R. Takagi, S. Minami, T. Nomoto, K. Ohishi, M.-T. Suzuki in Nature Physics (2023)

  3. Article

    Open Access

    Field-induced multiple metal-insulator crossovers of correlated Dirac electrons of perovskite CaIrO3

    The interplay between electron correlation and topology of relativistic electrons may lead to a fascinating stage of the research on quantum materials and emergent functions. The emergence of various collectiv...

    R. Yamada, J. Fujioka, M. Kawamura, S. Sakai, M. Hirayama in npj Quantum Materials (2022)

  4. Article

    Open Access

    Strong-correlation induced high-mobility electrons in Dirac semimetal of perovskite oxide

    Electrons in conventional metals become less mobile under the influence of electron correlation. Contrary to this empirical knowledge, we report here that electrons with the highest mobility ever found in know...

    J. Fujioka, R. Yamada, M. Kawamura, S. Sakai, M. Hirayama in Nature Communications (2019)

  5. Article

    Open Access

    Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions

    Malic enzyme 1 (ME1) regulates one of the main pathways that provide nicotinamide adenine dinucleotide phosphate (NADPH), which is essential for cancer cell growth through maintenance of redox balance and bios...

    S Murai, A Ando, S Ebara, M Hirayama, Y Satomi, T Hara in Oncogenesis (2017)

  6. Article

    Open Access

    The utility of procalcitonin for the patients with infected pancreatic necrotic and pancreatic abscess

    T Adachi, Y Kishihara, H Okano, H Honzawa in Intensive Care Medicine Experimental (2015)

  7. No Access

    Article

    Early skin toxicity predicts better outcomes, and early tumor shrinkage predicts better response after cetuximab treatment in advanced colorectal cancer

    Cetuximab-containing treatments for metastatic colorectal cancer have been shown to have higher overall response rates and longer progression-free and overall survival than other systemic therapies. Cetuximab-...

    T. Kogawa, A. Doi, M. Shimokawa, T. M. Fouad, T. Osuga, F. Tamura in Targeted Oncology (2015)

  8. No Access

    Article

    Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia

    Sixty-two infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia (MLL-r ALL) were treated with the MLL03 protocol of the Japanese Pediatric Leukemia/Lymphoma Study Group: short-course intensive...

    K Koh, D Tomizawa, A Moriya Saito, T Watanabe, T Miyamura, M Hirayama in Leukemia (2015)

  9. No Access

    Article

    Widespread cortical and subcortical brain atrophy in Parkinson’s disease with excessive daytime sleepiness

    Our aim was to determine regional brain atrophy in Parkinson’s disease (PD) patients with excessive daytime sleepiness (EDS) using voxel-based morphometry (VBM). From 71 consecutive probable PD patients, nine ...

    S. Kato, H. Watanabe, J. Senda, M. Hirayama, M. Ito, N. Atsuta in Journal of Neurology (2012)

  10. No Access

    Article

    Pupillary autonomic dysfunction in multiple system atrophy and Parkinson’s disease: an assessment by eye-drop tests

    To compare pupillary autonomic dysfunction in multiple system atrophy (MSA) and Parkinson’s disease (PD).

    Fumitada Yamashita, M. Hirayama, T. Nakamura, M. Takamori in Clinical Autonomic Research (2010)

  11. No Access

    Article

    Rapid αβ TCR-mediated responses in γδ T cells transduced with cancer-specific TCR genes

    Adoptive T-cell transfer of in vitro cultured T cells derived from cancer patients with naturally developed immune responses has met with some success as an immunotherapeutic approach, although only a limited num...

    A Hiasa, H Nishikawa, M Hirayama, S Kitano, S Okamoto, H Chono, S S Yu in Gene Therapy (2009)

  12. No Access

    Article

    Electrophysiological features of late-onset transthyretin Met30 familial amyloid polyneuropathy unrelated to endemic foci

    Through the development of gene diagnostic techniques, late-onset transthyretin Met30-associated familial amyloid polyneuropathy (FAP TTR Met30) has been shown to be more prevalent than is generally believed.

    H. Koike, Y. Kawagashira, M. Iijima, M. Yamamoto, N. Hattori in Journal of Neurology (2008)

  13. No Access

    Article

    Long-term phenotypic, functional and genetic stability of cancer-specific T-cell receptor (TCR) αβ genes transduced to CD8+ T cells

    In adoptive T-cell transfer as an intervention for malignant diseases, retroviral transfer of T-cell receptor (TCR) genes derived from CD8+ cytotoxic T-lymphocyte (CTL) clones provides an opportunity to generate ...

    A Hiasa, M Hirayama, H Nishikawa, S Kitano, I Nukaya, S S Yu, J Mineno in Gene Therapy (2008)

  14. No Access

    Article

    Primary structures and gene organizations of two types of Wap65 from the pufferfish Takifugu rubripes

    We isolated two types of cDNA clone encoding hemopexin-like protein, fWap65-1 and fWap65-2, from the pufferfish Takifugu rubripes. The deduced amino acid sequence of fWap65-1 showed 66–67% identity with those of ...

    M. Hirayama, M. Nakaniwa, D. Ikeda, N. Hirazawa in Fish Physiology and Biochemistry (2003)

  15. No Access

    Article

    A case of true malignant histiocytosis: identification of histiocytic origin with use of immunohistochemical and immunocytogenetic methods

    We report here an autopsy case of true malignant histiocytosis. The patient was a 67-year-old woman who exhibited fever, wasting, hepatosplenomegaly, and progressive pancytopenia. The bone marrow aspiration d...

    T. Sato, T. Terui, K. Kogawa, Y. Nagaoka, Y. Sato, S. Iyama in Annals of Hematology (2002)

  16. No Access

    Article

    Successful unrelated BMT in a patient with Kostmann syndrome complicated by pre-transplant pulmonary ‘bacterial’ abscesses

    Kostmann syndrome, severe congenital neutropenia, is often associated with life-threatening bacterial infections. A 5-year-old girl with Kostmann syndrome developed pulmonary abscesses. She was refractory to g...

    H Toyoda, E Azuma, H Hori, M Hirayama, M Kobayashi, K Isogai in Bone Marrow Transplantation (2001)

  17. No Access

    Article

    Low cardiac 123I-MIBG uptake in late-onset familial amyloid polyneuropathy type I (TTR Met30)

    H. Watanabe, K. Misu, M. Hirayama, N. Hattori, T. Yoshihara in Journal of Neurology (2001)

  18. No Access

    Article

    Quantitative evaluation of the enhanced green fluorescent protein displayed on the cell surface of Saccharomyces cerevisiae by fluorometric and confocal laser scanning microscopic analyses

    The number of foreign protein molecules expressed on the cell surface of the budding yeast Saccharomyces cerevisiae by cell surface engineering was quantitatively evaluated using enhanced green fluorescent prote...

    S. Shibasaki, M. Ueda, T. Iizuka, M. Hirayama in Applied Microbiology and Biotechnology (2001)

  19. No Access

    Article

    Late-onset unilateral renal dysfunction combined with non-insulin-dependent diabetes mellitus and bronchial asthma following allogeneic bone marrow transplantation for acute lymphoblastic leukemia in a child

    We report a child with T cell acute lymphoblastic leukemia who developed late-onset multiple complications after allogeneic bone marrow transplantation from an HLA-matched sibling. The preparative regimen cons...

    M Hirayama, E Azuma, T Kumamoto, J Qi, M Kobayashi, Y Komada in Bone Marrow Transplantation (1998)

  20. No Access

    Article

    IL-2-activated murine newborn liver NK cells enhance engraftment of hematopoietic stem cells in MHC-mismatched recipients

    To explore the modulatory effects of IL-2-activated NK cells on hematopoietic stem cell (HSC) engraftment further, we used fresh newborn liver cells (NLC) and IL-2-activated newborn liver cells (ANLC) as combi...

    M Hirayama, C Genyea, A Brownell, J Kaplan in Bone Marrow Transplantation (1998)

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