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Article
On the coexistence of convergence and divergence phenomena for integral averages and an application to the Fourier–Haar series
Let \(C,D\subset \mathbb{N}\) C , D ...
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Article
Spontaneous topological Hall effect induced by non-coplanar antiferromagnetic order in intercalated van der Waals materials
In ferromagnets, an electric current generally induces a transverse Hall voltage in proportion to the internal magnetization. This effect is frequently used for the electrical readout of the spin-↑ and spin-↓ ...
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Article
Open AccessField-induced multiple metal-insulator crossovers of correlated Dirac electrons of perovskite CaIrO3
The interplay between electron correlation and topology of relativistic electrons may lead to a fascinating stage of the research on quantum materials and emergent functions. The emergence of various collectiv...
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Article
Open AccessStrong-correlation induced high-mobility electrons in Dirac semimetal of perovskite oxide
Electrons in conventional metals become less mobile under the influence of electron correlation. Contrary to this empirical knowledge, we report here that electrons with the highest mobility ever found in know...
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Article
Open AccessInhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions
Malic enzyme 1 (ME1) regulates one of the main pathways that provide nicotinamide adenine dinucleotide phosphate (NADPH), which is essential for cancer cell growth through maintenance of redox balance and bios...
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Article
Open AccessThe utility of procalcitonin for the patients with infected pancreatic necrotic and pancreatic abscess
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Article
Early skin toxicity predicts better outcomes, and early tumor shrinkage predicts better response after cetuximab treatment in advanced colorectal cancer
Cetuximab-containing treatments for metastatic colorectal cancer have been shown to have higher overall response rates and longer progression-free and overall survival than other systemic therapies. Cetuximab-...
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Article
Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia
Sixty-two infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia (MLL-r ALL) were treated with the MLL03 protocol of the Japanese Pediatric Leukemia/Lymphoma Study Group: short-course intensive...
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Article
Widespread cortical and subcortical brain atrophy in Parkinson’s disease with excessive daytime sleepiness
Our aim was to determine regional brain atrophy in Parkinson’s disease (PD) patients with excessive daytime sleepiness (EDS) using voxel-based morphometry (VBM). From 71 consecutive probable PD patients, nine ...
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Article
Pupillary autonomic dysfunction in multiple system atrophy and Parkinson’s disease: an assessment by eye-drop tests
To compare pupillary autonomic dysfunction in multiple system atrophy (MSA) and Parkinson’s disease (PD).
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Article
Rapid αβ TCR-mediated responses in γδ T cells transduced with cancer-specific TCR genes
Adoptive T-cell transfer of in vitro cultured T cells derived from cancer patients with naturally developed immune responses has met with some success as an immunotherapeutic approach, although only a limited num...
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Article
Electrophysiological features of late-onset transthyretin Met30 familial amyloid polyneuropathy unrelated to endemic foci
Through the development of gene diagnostic techniques, late-onset transthyretin Met30-associated familial amyloid polyneuropathy (FAP TTR Met30) has been shown to be more prevalent than is generally believed.
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Article
Long-term phenotypic, functional and genetic stability of cancer-specific T-cell receptor (TCR) αβ genes transduced to CD8+ T cells
In adoptive T-cell transfer as an intervention for malignant diseases, retroviral transfer of T-cell receptor (TCR) genes derived from CD8+ cytotoxic T-lymphocyte (CTL) clones provides an opportunity to generate ...
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Article
Primary structures and gene organizations of two types of Wap65 from the pufferfish Takifugu rubripes
We isolated two types of cDNA clone encoding hemopexin-like protein, fWap65-1 and fWap65-2, from the pufferfish Takifugu rubripes. The deduced amino acid sequence of fWap65-1 showed 66–67% identity with those of ...
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Article
A case of true malignant histiocytosis: identification of histiocytic origin with use of immunohistochemical and immunocytogenetic methods
We report here an autopsy case of true malignant histiocytosis. The patient was a 67-year-old woman who exhibited fever, wasting, hepatosplenomegaly, and progressive pancytopenia. The bone marrow aspiration d...
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Article
Successful unrelated BMT in a patient with Kostmann syndrome complicated by pre-transplant pulmonary ‘bacterial’ abscesses
Kostmann syndrome, severe congenital neutropenia, is often associated with life-threatening bacterial infections. A 5-year-old girl with Kostmann syndrome developed pulmonary abscesses. She was refractory to g...
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Article
Low cardiac 123I-MIBG uptake in late-onset familial amyloid polyneuropathy type I (TTR Met30)
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Article
Quantitative evaluation of the enhanced green fluorescent protein displayed on the cell surface of Saccharomyces cerevisiae by fluorometric and confocal laser scanning microscopic analyses
The number of foreign protein molecules expressed on the cell surface of the budding yeast Saccharomyces cerevisiae by cell surface engineering was quantitatively evaluated using enhanced green fluorescent prote...
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Article
Late-onset unilateral renal dysfunction combined with non-insulin-dependent diabetes mellitus and bronchial asthma following allogeneic bone marrow transplantation for acute lymphoblastic leukemia in a child
We report a child with T cell acute lymphoblastic leukemia who developed late-onset multiple complications after allogeneic bone marrow transplantation from an HLA-matched sibling. The preparative regimen cons...
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Article
IL-2-activated murine newborn liver NK cells enhance engraftment of hematopoietic stem cells in MHC-mismatched recipients
To explore the modulatory effects of IL-2-activated NK cells on hematopoietic stem cell (HSC) engraftment further, we used fresh newborn liver cells (NLC) and IL-2-activated newborn liver cells (ANLC) as combi...