Chirurgisches Forum und DGAV Forum 2009
für experimentelle und klinische Forschung 126. Kongress der Deutschen Gesellschaft für Chirurgie München, 28.04.-01.05.2009
Article
VEGF induces normal or aberrant angiogenesis depending on its dose in the microenvironment around each producing cell in vivo. This transition depends on the balance between VEGF-induced endothelial stimulatio...
Article
We present a novel method to support precise insertion of engineered osteochondral grafts by pulling from the bone layer, thereby minimizing iatrogenic damage associated with direct manipulation of the cartila...
Book and Conference Proceedings
für experimentelle und klinische Forschung 126. Kongress der Deutschen Gesellschaft für Chirurgie München, 28.04.-01.05.2009
Book and Conference Proceedings
für experimentelle und klinische Forschung 125. Kongress der Deutschen Gesellschaft für Chirurgie Berlin, 22.04. – 25.04.2008
Article
Cancer cells’ growth in three-dimensional (3D) architectures promotes resistance to drugs, cytokines, or irradiation. We investigated effects of 3D culture as compared to monolayers (2D) on melanoma cells’ rec...
Chapter and Conference Paper
Background: Therapeutic angiogenesis aims at generating new blood vessels by delivering growth factors such as Vascular Endothelial Growth Factor (VEGF), and thus is a promising treatment for pat...
Book and Conference Proceedings
für experimentelle und klinische Forschung 123. Kongress der Deutschen Gesellschaft für Chirurgie Berlin, 02.05. – 05.05.2006
Chapter and Conference Paper
Chapter and Conference Paper
Introduction: Patients with advanced cancer display some immunodepression. We assess here humoral and cytotoxic T lymphocyte responsiveness in melanoma patients undergoing active specific immunotherapy trials and...
Article
Ausgedehnte osteochondrale Defekte erfordern eine Reparatur des Knorpels und des subchondralen Knochens. Wir erzeugten osteochondrales Ersatzgewebe mittels Tissue Engineering. 7×5×5 mm große standardisierte De...
Article
Chapter and Conference Paper
Tissue engineering has the potential to support many surgical procedures by providing functional grafts upon demand. However, the production of tissues remains a complex process in which the regulatory role of...
Chapter and Conference Paper
Introduction: Tumor immunotherapy requires strong adjuvants capable of inducing CTL responses and of breaking tolerance towards tumor-associated antigens (TAA). Clinical studies with soluble peptid...
Article
Tumour-associated antigens (TAA)-specific vaccination requires highly immunogenic reagents capable of inducing cytotoxic T cells (CTL). Soluble peptides are currently used in clinical applications despite an a...
Chapter and Conference Paper
Zielsetzung: In einem modernen Informatikumfeld sind viele Schnittstellen im Einsatz. Die aktuellen Schnittstellen werden in einem grösseren Krankenhaus analysiert. Wir haben gefragt, ob in einer...
Chapter and Conference Paper
Hintergrund: Das Ziel dieser Studie ist es, mittels der quantitativen real-time PCR (Taqman) durch den Nachweis von mRNA des Tumormarkers CEA und des Zytokeratines CK20 Karzinomzellen in Blut und...
Chapter and Conference Paper
Zielsetzung: Die Kommunikation zwischen Krankenhäusern und Arztpraxen kann heute bereits elektronisch abgewickelt werden. Wir haben in Europa verfügbare elektronische Kommunikationslösungen zwisc...
Chapter and Conference Paper
Introduction: MAGE tumor associated antigens (TAA) belong to the so called cancer/testis TAA family characterized by expression in different types of cancer including non-small cell lung cancer (...
Chapter and Conference Paper
Adult human articular chondrocytes (AHAC) redifferentiated by monolayer expansion are known to have a limited ability to re-enter the differentiation program and generate hyaline cartilage tissue ex vivo. We h...
Chapter and Conference Paper
Introduction: Immunodominant epitopes from tumor associated antigens (TAA) are currently used as soluble peptides (SP) in clinical trials in spite of an acknowledged low immunogenicity. We asked ...