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Article
Application of age estimation methods based on teeth eruption: how easy is Olze method to use?
The development of new methods for age estimation has become with time an urgent issue because of the increasing immigration, in order to estimate accurately the age of those subjects who lack valid identity d...
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Article
Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes
We reported that complement cascade (CC) becomes activated in bone marrow (BM) during mobilization of hematopoietic stem/progenitor cells (HSPCs) induced by granulocyte colony-stimulating factor (G-CSF) and C5...
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Article
A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice
Epistatic interactions between the non-autoimmune strains 129 and C57BL/6 (B6), used for generating gene-targeted animals, can induce a lupus-like disease. Genome-wide scan analyses of testcross progeny betwee...
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Article
Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus
Systemic lupus erythematosus is an autoimmune disease in which complex interactions between genes and environmental factors determine the disease phenotype. We have shown that genes from the non-autoimmune str...
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Chapter and Conference Paper
Etablierung von CMRT’s (Clinic Modelling Randomised Trials) im Knock-out-Mausmodell: Einfluß des Komplementsystems in der postoperativen Peritonitis und Sepsis
Introduction: To investigate the pathophysiology of postoperative peritonitis and sepsis before conducting a costly clinical trial, experiments in knock-out (KO) animal models were performed (fre...
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Article
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
Serum amyloid P component (SAP), a highly conserved plasma protein named for its universal presence in amyloid deposits1, is the single normal circulating protein that shows specific calcium-dependent binding to ...
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Article
Murine D17H6S45 (Rd) gene: polymorphism and overlap with complement factor B
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Article
Cyclosporin in Behçet's disease: Results in 16 patients after 24 months of therapy
The aim of this study was to evaluate the usefulness of cyclosporin in Behçet's disease. Sixteen subjects (10 males and 6 females; mean age 25.2 years) affected by the complete type of Behçet's syndrome receiv...
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Article
Seronegative spondyloarthropathy associated with megarectum
In this report we describe a case of a 19-year-old man with a two-year history of polyarthritis affecting the lower limbs and dactylitis of the toes. His clinical picture fulfilled the new European diagnostic ...