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Article
Methylation of the Human AR Locus Does Not Correlate with the Presence of Inactivated X Chromosome in Induced Pluripotent Stem Cells
The process of dosage compensation of genes occurs in the female mammalian cells during early embryonic development: one of the two X chromosomes becomes transcriptionally inactive and is subsequently inherite...
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Article
Molecular Mechanisms of Spinocerebellar Ataxia Type 1
Polyglutamine (polyQ) disorders are severe forms of inherited neurodegenerative pathologies caused by the expansion of CAG repeats in specific genes accompanied by abnormal elongation of the polyglutamic resid...
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Article
Genetic cell reprogramming: A new technology for basic research and applied usage
Gene function disclosure and the development of modern technologies of genetic manipulations offered the possibility of genetic reprogramming application to alter cell specialization. With the involvement of a...