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  1. No Access

    Article

    RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease

    Receptor for AGE (RAGE) is a member of the immunoglobulin superfamily that engages distinct classes of ligands. The biology of RAGE is driven by the settings in which these ligands accumulate, such as diabete...

    L. G. Bucciarelli, T. Wendt, L. Rong, E. Lalla… in Cellular and Molecular Life Sciences CMLS (2002)

  2. No Access

    Article

    RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response

    The receptor for advanced glycation end products (RAGE) and its proinflammatory S100/calgranulin ligands are enriched in joints of subjects with rheumatoid arthritis (RA) and amplify the immune/inflammatory re...

    M A Hofmann, S Drury, B I Hudson, M R Gleason, W Qu, Y Lu, E Lalla… in Genes & Immunity (2002)

  3. No Access

    Article

    A Recombinant Classical Swine Fever Virus with a Marker Insertion in the Internal Ribosome Entry Site

    Based on an infectious cDNA clone of classical swine fever virus (CSFV) strain Alfort/187 (Ruggli et al., J Virol 70, 3478–3487, 1996) a full-length cDNA was constructed harbouring a nonviral 44 base insertion in...

    C. Moser, A. Bosshart, J.-D. Tratschin, M. A. Hofmann in Virus Genes (2001)

  4. No Access

    Article

    Classical swine fever virus is genetically stable in vitro and in vivo

     Phylogenetic analyses of large numbers of classical swine fever strains have revealed a high degree of sequence conservation in the genomic regions examined, suggesting either a recent common ancestor or a lo...

    H. Vanderhallen, C. Mittelholzer, M. A. Hofmann, F. Koenen in Archives of Virology (1999)

  5. Article

    Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kB

    Increased oxidative stress and subsequent activation of the transcription factor NF-kB has been linked to the development of late diabetic complications. To determine whether oxidative stress dependent NF-kB ...

    M. A. Hofmann, S. Schiekofer, B. Isermann, M. Kanitz, M. Henkels, M. Joswig… in Diabetologia (1999)

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  6. No Access

    Article

    Rapid characterization of new pestivirus strains by direct sequencing of PCR-amplified cDNA from the 5′ noncoding region

    Reverse transcription coupled with the polymerase chain reaction (RT-PCR) was used for the rapid laboratory diagnosis of pestivirus infections. A direct DNA sequencing method was developed for the analysis of ...

    M. A. Hofmann, K. Brechtbühl, N. Stäuber in Archives of Virology (1994)

  7. Chapter and Conference Paper

    Role of subgenomic minus-strand RNA in coronavirus replication

    Coronavirus subgenomic minus-strand RNAs (negative-strand copies of the 3′ coterminal subgenomic mRNAs) probably function in mRNA amplification by serving as templates for transcription from internal (intergen...

    Dr. D. A. Brian, R.-Y. Chang, M. A. Hofmann, P. B. Sethna in Positive-Strand RNA Viruses (1994)

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