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    Article

    Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation

    Although CD133 has been considered to be a molecular marker for cancer stem cells, its functional roles in tumorigenesis remain unclear. We here examined the molecular basis behind CD133-mediated signaling. Kn...

    O Shimozato, M Waraya, K Nakashima, H Souda, N Takiguchi, H Yamamoto… in Oncogene (2015)