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    Article

    The Trop-2 signalling network in cancer growth

    Our findings show that upregulation of a wild-type Trop-2 has a key controlling role in human cancer growth, and that tumour development is quantitatively driven by Trop-2 expression levels. However, little is...

    E Guerra, M Trerotola, A L Aloisi, R Tripaldi, G Vacca, R La Sorda, R Lattanzio in Oncogene (2013)

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    Article

    Upregulation of Trop-2 quantitatively stimulates human cancer growth

    Trop-2 is a calcium signal transducer that is associated with transformed cell growth in experimental systems. However, its role in human cancer remains essentially unknown. In this study, we profiled Trop-2 e...

    M Trerotola, P Cantanelli, E Guerra, R Tripaldi, A L Aloisi, V Bonasera in Oncogene (2013)