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Article
Patientenspezifische Instrumente und Implantate beim Teilgelenkersatz des Kniegelenkes (ConforMIS iUni, iDuo)
Die Knieendoprothetik ist eine erfolgreiche Standardoperation in der orthopädischen Chirurgie. Etwa 20 % der Patienten sind jedoch mit dem klinischen Ergebnis unzufrieden. Sie haben Schmerzen und erreichen nic...
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Article
Dynamic in vitro analysis of tractile forces of the anterior cruciate ligament (ACL) transplant using patellar and semitendinosus muscle tendon: a cadaver study
The presented biomechanical study focused on the in vitro analysis of tractile forces working on the anterior cruciate ligament (ACL) and the ACL transplants, respectively, using a semitendinosus and/or patell...
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Article
Biological activity and migration of wear particles in the knee joint: an in vivo comparison of six different polyethylene materials
Wear of polyethylene causes loosening of joint prostheses because of the particle mediated activity of the host tissue. It was hypothesized that conventional and crosslinked polyethylene particles lead to simi...
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Article
Vorgehen bei schmerzhafter Kappenprothese
Der Oberflächenersatz des Hüftgelenks ist seit 10 Jahren wieder im Fokus der Hüftgelenkendoprothetik. Trotz verbesserter Technologien und Materialien wurden allerdings vermehrt Komplikationen und Lockerungsrat...
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Article
Zementfreie Endoprothetik des Hüftgelenks
Die Ergebnisse der zementierten Endoprothetik am Hüftgelenk erscheinen beim älteren Patienten exzellent. Bei Jüngeren ist das Ergebnis deutlich schlechter. Aus diesem Grunde wurden neue Konzepte in der Endopro...
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Article
Timing of cervical spine stabilisation and outcome in patients with rheumatoid arthritis
One complication of rheumatoid arthritis (RA) is the involvement of the cervical spine (CS). Although prophylactic stabilisation is recommended, the timing at which this should occur is poorly defined. The aim...
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Article
Selective inhibition of platelets by the GPIIb/IIIa receptor antagonist Tirofiban reduces leukocyte-endothelial cell interaction in murine antigen-induced arthritis
Inflammation is associated with the invasion of leukocytes into affected tissues and with the up-regulation of platelet activation and adhesion. Assuming that leukocyte accumulation is linked to platelet aggre...
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Article
Endothelial iNOS versus platelet iNOS: Responsibility for the platelet/leukocyte endothelial cell interaction in murine antigen induced arthritis in vivo
Since an increase of platelet-endothelial cell interactions has been observed in mice with Antigen- induced-Arthritis (AiA) as well as an increase of NO expression, the aim of our study was to investigate in v...
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Article
Diagnosespezifische Unterschiede der Kniegelenkgeometrie
Bei arthrotischen Deformitäten mit veränderter Kniegelenkgeometrie kann es bei Knieprothesensystemen mit intramedullärer Achsausrichtung oder langstieligen Prothesenkomponenten zur unerwünschten Zwangsführung ...
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Article
Effects of ibandronate on inflammation in mouse antigen-induced arthritis
Objective: To investigate the effects of ibandronate, a novel aminobisphosphonate, on inflammation as well as leukocyte-endothelial cell interaction in mouse antigen-induced arthritis (AiA). Material and Treatme...
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Article
Open AccessOrthogonal polarisation spectral imaging as a new tool for the assessment of antivascular tumour treatment in vivo: a validation study
Tumour angiogenesis plays a key role in tumour growth, formation of metastasis, detection and treatment of malignant tumours. Recent investigations provided increasing evidence that quantitative analysis of tu...