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  1. Article

    Open Access

    Identification of thymidylate synthase as a potential therapeutic target for lung cancer

    Thymidylate synthase (TS), a key enzyme in the de novo synthesis of thymidine, is an important chemotherapeutic target for malignant tumours including lung cancer. Although inhibition of TS has an antiproliferati...

    K Takezawa, I Okamoto, S Tsukioka, J Uchida, M Kiniwa in British Journal of Cancer (2010)