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  1. Article

    Correction to: CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation

    Following publication of their article “CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation”, the authors reported an error in Fig.6b. α-Tubulin image of rC...

    C-C Chang, M-H Yang, B-R Lin, S-T Chen, S-H Pan, M Hsiao… in Cell Death & Differentiation (2019)

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  2. Article

    Open Access

    Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

    Lung cancer is the leading cause of cancer death worldwide. Recently, epigenetic dysregulation has been known to promote tumor progression and therefore may be a therapeutic target for anticancer therapy. JARI...

    Kuang-Tai Kuo, Wen-Chien Huang, Oluwaseun Adebayo Bamodu… in Clinical Epigenetics (2018)

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  3. Article

    Erratum: Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association

    Correction to: Oncogene (2016) 35, 3387–3398; doi:10.1038/onc.2015.397; published online 26 October 2015 Since the publication of this article the authors noticed an inadvertent mistake in the representative p...

    Y-C Yang, T-Y Cheng, S-M Huang, C-Y Su, P-W Yang, J-M Lee, C-K Chen, M Hsiao… in Oncogene (2017)

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  4. No Access

    Article

    Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90–EGFR association

    Secondary mutation of epidermal growth factor receptor (EGFR) resulting in drug resistance is one of the most critical issues in lung cancer therapy. Several drugs are being developed to overcome EGFR tyrosine...

    Y-C Yang, T-Y Cheng, S-M Huang, C-Y Su, P-W Yang, J-M Lee, C-K Chen, M Hsiao… in Oncogene (2016)

  5. Article

    Open Access

    MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

    MicroRNAs (miRNAs) comprise a class of short, non-coding RNAs that regulate protein synthesis through posttranscriptional modifications. In this study, we found significant upregulation of miR-18a in prostate ...

    T-I Hsu, C-H Hsu, K-H Lee, J-T Lin, C-S Chen, K-C Chang, C-YJ Su, M Hsiao… in Oncogenesis (2014)

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  6. No Access

    Article

    Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78

    Lung cancer is the leading cause of cancer deaths and is the most occurring malignancy worldwide. Unraveling the molecular mechanisms involved in lung tumorigenesis will greatly improve therapy. During early t...

    H-Y Tsai, Y-F Yang, A T Wu, C-J Yang, Y-P Liu, Y-H Jan, C-H Lee, Y-W Hsiao… in Oncogene (2013)

  7. Article

    Open Access

    CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation

    CCN family protein 2 (CCN2), also known as connective tissue growth factor, is a secreting protein that modulates multiple cellular events. We previously demonstrated the metastasis-suppressive effect of CCN2 ...

    C-C Chang, M-H Yang, B-R Lin, S-T Chen, S-H Pan, M Hsiao… in Cell Death & Differentiation (2013)

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  8. No Access

    Article

    MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol

    Resveratrol, a phytochemical found in various plants and Chinese herbs, is associated with multiple tumor-suppressing activities, has been tested in clinical trials. However, the molecular mechanisms involved ...

    Y-H Yu, H-A Chen, P-S Chen, Y-J Cheng, W-H Hsu, Y-W Chang, Y-H Chen, Y Jan… in Oncogene (2013)

  9. No Access

    Article

    RUNX3-mediated transcriptional inhibition of Akt suppresses tumorigenesis of human gastric cancer cells

    Activation of Akt signaling pathway has been suggested involving in chemoresistance, metastasis and tumorigenesis of gastric cancer. However, the mechanism of Akt regulation in gastric cancer is not fully unde...

    F-C Lin, Y-P Liu, C-H Lai, Y-S Shan, H-C Cheng, P-I Hsu, C-H Lee, Y-C Lee… in Oncogene (2012)

  10. Article

    Open Access

    WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β

    WW domain-containing oxidoreductase (WWOX), a putative tumour suppressor, is suggested to be involved in the hyperphosphorylation of Alzheimer's Tau. Tau is a microtubule-associated protein that has an importa...

    H-Y Wang, L-I Juo, Y-T Lin, M Hsiao, J-T Lin, C-H Tsai… in Cell Death & Differentiation (2012)

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  11. No Access

    Article

    TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer

    We integrated four gene expression profile data sets, namely two different pair-matched stage I lung adenocarcinoma data sets, secondary metastatic tumors vs benign tumors and lung tumor metastasizes to the br...

    M-C Shih, J-Y Chen, Y-C Wu, Y-H Jan, B-M Yang, P-J Lu, H-C Cheng, M-S Huang… in Oncogene (2012)

  12. Article

    Incidence and epidemiology of spinal cord injury within a closed American population: the United States military (2000–2009)

    Cohort study

    A J Schoenfeld, B McCriskin, M Hsiao, R Burks in Spinal Cord (2011)

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  13. No Access

    Article

    MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

    MicroRNAs (miRNAs) make up a novel class of gene regulators; they function as oncogenes or tumor suppressors by targeting tumor-suppressor genes or oncogenes. A recent study that analysed a large number of hum...

    K-H Lee, Y-L Chen, S-D Yeh, M Hsiao, J-T Lin, Y-G Goan, P-J Lu in Oncogene (2009)

  14. No Access

    Chapter and Conference Paper

    RETRACTED CHAPTER: The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies

    The Editors have retracted this conference paper at the request of the corresponding author due to substantial overlap with a previously published article by the same authors [1]. This conference paper is ther...

    J.-H. Huang, H. J. Parab, R. S. Liu… in 13th International Conference on Biomedica… (2009)

  15. No Access

    Chapter and Conference Paper

    Characterization of Functional Nanomaterials in Cosmetics and its Cytotoxic Effects

    The ultraviolet (UV) rays from sun are generally divided in three types such as UVA (315~400 nm), UVB (280~315 nm) and UVC (100~280 nm). Among these, the UVC rays with the highest energy get absorbed completel...

    J.-H. Huang, H. J. Parab, R. S. Liu… in 13th International Conference on Biomedica… (2009)

  16. No Access

    Article

    Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma

    A comprehensive microarray analysis of hepatocellular carcinoma (HCC) revealed distinct synexpression patterns during intrahepatic metastasis. Recent evidence has demonstrated that synexpression group member g...

    Y-L Liao, Y-M Sun, G-Y Chau, Y-P Chau, T-C Lai, J-L Wang, J-T Horng, M Hsiao… in Oncogene (2008)

  17. No Access

    Article

    ACAT1 is not associated with Alzheimer's disease in two independent family-based samples

    L Bertram, M Hsiao, K Mullin, M Parkinson, R Menon, T J Moscarillo… in Molecular Psychiatry (2005)

  18. No Access

    Article

    Beare-Stevenson Cutis Gyrata Syndrome with Chiari Malformation

    T. J. Wang, K. S. Hung, P. K. T. Chen, W. L. Chuang, T. Y. Shih… in Acta Neurochirurgica (2002)