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  1. No Access

    Chapter and Conference Paper

    Measuring the Time Impact of Web Accessibility Barriers on Blind Users: A Pilot Study

    As governments around the world increase or clarify the requirements related to web accessibility for public accommodations, they often require some level of cost-benefit analysis for the proposed regulation....

    M. Griffith, B. Wentz, J. Lazar in Designing for Inclusion (2020)

  2. No Access

    Article

    How do I manage hyperglycemia/post-transplant diabetes mellitus after allogeneic HSCT

    Allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients frequently develop glucose intolerance and post-transplant diabetes mellitus (PTDM). The clinical importance of PTDM and its detrimenta...

    S Fuji, A Rovó, K Ohashi, M Griffith, H Einsele, M Kapp in Bone Marrow Transplantation (2016)

  3. Article

    Open Access

    A genomic analysis of Philadelphia chromosome-negative AML arising in patients with CML

    K Krysiak, M J Christopher, Z L Skidmore, R T Demeter, V Magrini in Blood Cancer Journal (2016)

  4. No Access

    Article

    U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing

    We previously identified missense mutations in the U2AF1 splicing factor affecting codons S34 (S34F and S34Y) or Q157 (Q157R and Q157P) in 11% of the patients with de novo myelodysplastic syndrome (MDS). Although...

    T Okeyo-Owuor, B S White, R Chatrikhi, D R Mohan, S Kim, M Griffith, L Ding in Leukemia (2015)

  5. No Access

    Article

    Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer

    The drug fluorouracil (5-FU) is a widely used antimetabolite chemotherapy in the treatment of colorectal cancer. The gene uridine monophosphate synthetase (UMPS) is thought to be primarily responsible for convers...

    M Griffith, J C Mwenifumbo, P Y Cheung, J E Paul, T J Pugh in The Pharmacogenomics Journal (2013)

  6. Article

    Artificial corneas: a regenerative medicine approach

    Corneal substitutes are being developed to address the shortage of human donor tissues as well as the current disadvantages in some clinical indications, which include immune rejection. In the past few years, ...

    M Griffith, W B Jackson, N Lagali, K Merrett, F Li, P Fagerholm in Eye (2009)

  7. No Access

    Article

    Expressed sequence tags from the Yukon ecotype of Thellungiella reveal that gene expression in response to cold, drought and salinity shows little overlap

    Thellungiella salsuginea (also known as T. halophila) is a close relative of Arabidopsis that is very tolerant of drought, freezing, and salinity and may be an appropriate model to identify the molecular mechanis...

    C.E. Wong, Y. Li, B.R. Whitty, C. Díaz-Camino, S.R. Akhter in Plant Molecular Biology (2005)

  8. No Access

    Chapter and Conference Paper

    The Development and Optimisation of High Bandwidth Bimorph Deformable Mirrors

    Our first mirror designs were based on a standard bimorph construction and exhibited a resonant frequency of 1 kHz with a maximum stroke of ±5 μm. These devices were limited by the requirement to have a “dead ...

    D. Rowe, L. Laycock, M. Griffith, N. Archer in Adaptive Optics for Industry and Medicine (2005)

  9. Article

    Open Access

    Trends in mortality for cancers, comparing multiple- and underlying-cause rates, in an English population 1979–1999

    In compiling official mortality statistics, rules for selecting the underlying cause of death have changed twice in the last 20 years in England. Mortality statistics for most types of cancer were not greatly ...

    M J Goldacre, M E Duncan, P Cook-Mozaffari, M Griffith in British Journal of Cancer (2004)

  10. Article

    Open Access

    Childhood cancer incidence in a cohort of twin babies

    We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (St...

    M F G Murphy, D Whiteman, K Hey, M Griffith, L Gill in British Journal of Cancer (2001)

  11. No Access

    Article

    Genetic studies of antifreeze proteins and their correlation with winter survival in wheat

    Antifreeze proteins (AFPs) accumulate in the leaves of winter cereals during cold acclimation, where they may inhibit ice recrystallization during freezing and thawing cycles and provide nonspecific disease re...

    J.U. Chun, X.M. Yu, M. Griffith in Euphytica (1998)

  12. No Access

    Chapter and Conference Paper

    Calibration Issues in the Search for Large-Scale Anisotropies in the 87 Green Bank and Parkes-Mit-Nrao Surveys

    Until recently, there were no large scale radio surveys which were sensitive enough to have a sufficient number of sources to detect a dipole anisotropy. The 87 Green Bank (87GB) (Gregory and Condon, 1991) and...

    F. Crawford, I. Avruch, A. Fletcher, M. Griffith, B. Burke in Observational Cosmology (1998)

  13. No Access

    Chapter

    Characterization of Antifreeze Proteins from Winter Rye

    When winter settles upon the landscape and the soil and lakes have frozen, it is important to realize that many biological organisms have frozen too. After a period of acclimatization to cold autumn temperatur...

    M. Griffith, A. Mlynarz, W. C. Hon, F. Sicheri, D. S. C. Yang in Plant Cold Hardiness (1997)

  14. No Access

    Article

    Immunogold localization of glucanase-like antifreeze protein in cold acclimated winter rye

    Apoplastic antifreeze proteins (AFPs) accumulate in winter rye (Secale cereale L. cv. Musketeer) leaves during cold acclimation. Two of the rye AFPs with molecular masses of 32 and 35 kDa are similar in their ami...

    K. Pihakaski-Maunsbach, M. Griffith, M. Antikainen, A. B. Maunsbach in Protoplasma (1996)

  15. No Access

    Chapter

    Vegetative Development

    Arabidopsis thaliana is a rosette annual with separate vegetative and reproductive growth phases. Vegetative development is characterized by the production of rosette leaves in a phyllotactic spiral with little ...

    John Bowman, J. D. Callos, F. J. Behringer, J. Vasinda, D. Stewart in Arabidopsis (1994)

  16. No Access

    Article

    Ultrapure plasma factor VIII produced by anti-FVIIIc immunoaffinity chromatography and solvent/detergent viral inactivation. Characterization of the Method M process and Hemofil M antihemophilic factor (human)

    The Method M process was developed to reduce the risk of virus transmission associated with the therapeutic use of AHF products. The Method M process uses a powerful viral inactivation approach and consistentl...

    M. Griffith in Annals of Hematology (1991)

  17. No Access

    Article

    In-process controls and characterization of recombinate antihemophilic factor (recombinant)

    M. Griffith, H. Kingdon, S. -L. Liu, W. Burkart in Annals of Hematology (1991)

  18. No Access

    Article

    Functional xylem anatomy in root-shoot junctions of six cereal species

    In cereals, the formation of safety zones in the root-shoot junction could protect the vessels of roots from embolism originating in the shoot. The root-shoot junction was examined both anatomically, with a li...

    R. Aloni, M. Griffith in Planta (1991)

  19. No Access

    Article

    Phytoplankton community structure and distribution in the nearshore zone of Lake Ontario

    Spatial and temporal distributions of phytoplankton were studied during 1979 in the nearshore zone of Lake Ontario. Genera such as Dinobryon, Oscillatoria, and Gymnodinium tended to be found at discrete depths wh...

    G. D. Haffner, M. Griffith, P. D. N. Hebert in Hydrobiologia (1984)

  20. No Access

    Chapter

    The Effects of Low Temperature growth on the Structure of Photosystem II

    When thylakoids are isolated from winter rye grown at 5°C, they exhibit higher PSII activities over the temperature range 8–26°C than thylakoids isolated from plants grown at 20°C (Huner, Hopkins, unpublished). H...

    M. Griffith, M. Krol, E. L. Camm, N. P. A. Huner in Advances in Photosynthesis Research (1984)