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  1. Article

    Open Access

    Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14–16, 2018; Vienna, Austria

    Here, we report on the outcome of the 2nd International Danube Symposium on advanced biomarker development that was held in Vienna, Austria, in early 2018. During the meeting, cross-speciality participants ass...

    M. S. Lim, Thomas Beyer, A. Babayan, M. Bergmann in Molecular Imaging and Biology (2020)

  2. No Access

    Article

    High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL

    S K Tasian, C Hurtz, G B Wertheim, N G Bailey, M S Lim, R C Harvey, I-M Chen in Leukemia (2017)

  3. No Access

    Article

    NPM-ALK phosphorylates WASp Y102 and contributes to oncogenesis of anaplastic large cell lymphoma

    Mechanisms by which NPM-ALK signaling regulates cell migration, invasion and contributes to the oncogenesis of anaplastic large cell lymphoma (ALCL) are not completely understood. In an attempt to identify nov...

    C A Murga-Zamalloa, V Mendoza-Reinoso, A A Sahasrabuddhe, D Rolland, S R Hwang in Oncogene (2017)

  4. No Access

    Article

    Novel ALK fusion in anaplastic large cell lymphoma involving EEF1G, a subunit of the eukaryotic elongation factor-1 complex

    G Palacios, T I Shaw, Y Li, R K Singh, M Valentine, J T Sandlund, M S Lim in Leukemia (2017)

  5. No Access

    Article

    Effects of Melatonin on Colchicine-Treated PLBs of Dendrobium sonia-28 Orchid

    Dendrobium hybrid orchid is popular in orchid commercial industry due to its short life cycle and ability to produce various types of flower colours. This study was conducted to identify ...

    M . S. Lim, J. J. J. Antony, S. M. Shahinul Islam in Applied Biochemistry and Biotechnology (2017)

  6. No Access

    Article

    Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation

    EZH2 (enhancer of zeste homolog 2) is a critical enzymatic subunit of the polycomb repressive complex 2 (PRC2), which trimethylates histone H3 (H3K27) to mediate gene repression. Somatic mutations, overexpress...

    A A Sahasrabuddhe, X Chen, F Chung, T Velusamy, M S Lim in Oncogene (2015)

  7. Article

    Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival

    Prostate apoptosis response protein 4 (Par-4) also known as PRKC apoptosis WT1 regulator is a tumor suppressor that selectively induces apoptosis in cancer cells. However, its post-translational regulation by ...

    X Chen, A A Sahasrabuddhe, P Szankasi, F Chung, V Basrur in Cell Death & Differentiation (2014)

  8. Article

    Open Access

    The role of front-line anthracycline-containing chemotherapy regimens in peripheral T-cell lymphomas

    Peripheral T-cell lymphomas (PTCLs) are a heterogenous group of aggressive non-Hodgkin’s lymphomas that are incurable in the majority of patients with current therapies. Outcomes associated with anthracycline-...

    R Briski, A L Feldman, N G Bailey, M S Lim, K Ristow, T M Habermann in Blood Cancer Journal (2014)

  9. No Access

    Article

    NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis

    Anaplastic large cell lymphoma (ALCL) is the most common type of pediatric peripheral T-cell lymphoma. In 70–80% of cases, the chromosomal aberration t(2;5)(p23;q35) results in the juxtaposition of anaplastic lym...

    S R P McDonnell, S R Hwang, V Basrur, K P Conlon, D Fermin, E Wey in Oncogene (2012)

  10. No Access

    Article

    A Novel Lateral Field Emission Triode for Microwave Application

    We propose a novel lateral field emission triode, which does not require any additional vacuum sealing process and exhibits superb field emitter triode performance. The purpose of this paper is to compare tita...

    C. M. Park, M. S. Lim, M. K. Han, Y. I. Choi in MRS Online Proceedings Library (2011)

  11. No Access

    Article

    The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma

    P M Bhende, S I Park, M S Lim, D P Dittmer, B Damania in Leukemia (2010)

  12. No Access

    Article

    Loss of Ubr1 promotes aneuploidy and accelerates B-cell lymphomagenesis in TLX1/HOX11-transgenic mice

    The TLX1/HOX11 homeobox gene was originally identified at the recurrent t(10;14)(q24;q11) translocation breakpoint, a chromosomal abnormality observed in 5–7% of T-cell acute lymphoblastic leukemias (T-ALLs). Pro...

    E Chen, Y T Kwon, M S Lim, I D Dubé, M R Hough in Oncogene (2006)

  13. No Access

    Article

    Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice

    Dysregulated expression of the homeobox gene, HOX11 is a frequent etiologic event in T-cell acute lymphoblastic leukemias. HOX11-transgenic mice (IgHμ-HOX11Tg)-expressing HOX11 in the B-cell compartment develop B...

    E Chen, M S Lim, S Rosic-Kablar, J Liu, P Jolicoeur, I D Dubé, M R Hough in Oncogene (2006)

  14. No Access

    Article

    Microstructural and mechanical stability of Cu-6 wt. % Ag alloy

    The microstructural and mechanical stability of Cu-6 wt. % Ag alloy obtained by cold rolling combined with intermediate heat treatments have been investigated. The stress-strain responses and fracture behavior...

    M. S. Lim, J. S. Song, S. I. Hong in Journal of Materials Science (2000)

  15. No Access

    Article

    Polycrystalline Silicon Single Electron Island by Excimer Laser Irradiation on a-Si Film

    We propose a novel fabrication method for a room temperature operating single-electron memory using the size and location controlled poly-Si island by lithographic technique and excimer laser annealing.

    C. -M. Park, J. -H. Jeon, M. -S. Lim, J. -S. Yoo in MRS Online Proceedings Library (1998)

  16. No Access

    Chapter

    Real-Time Implementation of QCELP Vocoder for speech and data in CDMA Cellular System Using TMS320C50 Fixed Point DSP Chip

    An variable rate QCELP speech coder was proposed for CDMA digital cellular system and QCELP algorithm has been chosen as the speech coder of digital cellular system in North America and Korea. ...

    J. W. kim, B. S. Yoon, W. M. Lee, S. J. Jang, M. S. Lim in Wireless Personal Communications (1997)

  17. No Access

    Chapter and Conference Paper

    Thin Filament-Linked Regulation in Vertebrate Smooth Muscle

    It is widely accepted that myosin-linked regulation, specifically the reversible phosphorylation of myosin, represents the primary Ca2+-dependent mechanism for the regulation of smooth muscle contraction. This me...

    M. P. Walsh, G. C. Scott-Woo, M. S. Lim in Calcium and Calcium Binding Proteins (1988)