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  1. Article

    Open Access

    Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer

    Ovarian cancer patients frequently develop chemotherapy resistance, limiting treatment options. We have previously shown that individuality in fibroblast growth factor 1 (FGF1) expression influences survival and ...

    Hugh A. Nicholson, Lynne Sawers, Rosemary G. Clarke in British Journal of Cancer (2022)

  2. Article

    Open Access

    ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells

    Clinical response to chemotherapy for ovarian cancer is frequently compromised by the development of drug-resistant disease. The underlying molecular mechanisms and implications for prescription of routinely p...

    Aparajitha Vaidyanathan, Lynne Sawers, Anne-Louise Gannon in British Journal of Cancer (2016)