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Open AccessDevelopment of a Patient-Reported Outcome Measure for Non-Alcoholic Steatohepatitis (NASH-CHECK): Results of a Qualitative Study
Non-alcoholic steatohepatitis (NASH) is a progressive form of non-alcoholic fatty liver disease characterized by excessive liver fat accumulation, inflammation, cell injury, and fibrosis. It is viewed as large...
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Article
Development and validation of the living with chronic obstructive pulmonary disease questionnaire
Available patient-reported outcome (PRO) measures for chronic obstructive pulmonary disease (COPD) focus primarily on impairment (symptoms) and activities (functioning). The purpose of the study was to develop...
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Article
Open AccessInterpreting scores on multiple sclerosis-specific patient reported outcome measures (the PRIMUS and U-FIS)
The PRIMUS is a Multiple Sclerosis (MS)-specific suite of outcome measures including assessments of QoL (PRIMUS QoL, scored 0-22) and activity limitations (PRIMUS Activities, scored 0-30). The U-FIS is a measu...
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Article
Open AccessPatient reported outcomes: looking beyond the label claim
The use of patient reported outcome scales in clinical trials conducted by the pharmaceutical industry has become more widespread in recent years. The use of such outcomes is particularly common for products d...
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Article
Open AccessRetraction Note: Psychometric characteristics of the ankylosing spondylitis quality of life questionnaire, short form 36 health survey, and functional assessment of chronic illness therapy-fatigue subscale
Retraction of Revicki DA, Rentz AM, Luo MP, Wong RL, Doward LC, McKenna SP: Psychometric characteristics of the ankylosing spondylitis quality of life questionnaire, short form 36 health survey, and functional...
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Open AccessPsychometric characteristics of the ankylosing spondylitis quality of life questionnaire, short form 36 health survey, and functional assessment of chronic illness therapy-fatigue subscale
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Article
Open AccessQuality of life in infants and children with atopic dermatitis: Addressing issues of differential item functioning across countries in multinational clinical trials
A previous study had identified 45 items assessing the impact of atopic dermatitis (AD) on the whole family. From these it was intended to develop two separate scales, one assessing impact on carers and the ot...
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Article
Open AccessTranslation and validation of non-English versions of the Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire
The Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire is a unidimensional, disease-specific measure developed in the UK and the Netherlands. This study describes its adaptation into other languages.
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Open AccessMeasuring the psychosocial consequences of screening
The last three decades have seen a dramatic rise in the implementation of screening programmes for cancer in industrialised countries. However, in contrast to screening for infectious diseases, most cancer scr...
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Article
A Review of Quality of Life in Alzheimer’s Disease
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The development of a quality of life instrument for use with post-menopausal women with urogenital atrophy in the UK and Sweden
Many post-menopausal women suffer from oestrogen deficiency. This can cause urogenital atrophy which leads to symptoms such as dyspareunia, dysuria, vaginal dryness and urge incontinence. Even though urogenita...
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Article
The QoL-AGHDA: An instrument for the assessment of quality of life in adults with growth hormone deficiency
Several studies have shown that growth hormone deficiency in adults leads to poor well-being and other clinical consequences, and that these improve when the hormone is replaced. However, the studies employed ...
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Article
The Development and Psychometric Properties of the MSQOL
This paper describes the development and testing of the UK version of the Migraine-Specific Quality-of-Life instrument (MSQOL), a measure designed to assess the quality of life of migraineurs. The work was par...
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Article
Quality-of-Life Assessment of Adults with Growth Hormone Deficiency
Growth hormone (GH) deficiency in adults affects many physiological functions. It may result in reduced muscle volume and strength, changes in body mass, lowered metabolic rate, low energy and sexual drive and...
