-
Article
Open AccessSpatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer
Pancreatic ductal adenocarcinoma is a lethal disease with limited treatment options and poor survival. We studied 83 spatial samples from 31 patients (11 treatment-naïve and 20 treated) using single-cell/nucle...
-
Article
Open AccessAuthor Correction: Comparative and demographic analysis of orang-utan genomes
-
Article
Open AccessComparative and demographic analysis of orang-utan genomes
The genome of the Southeast Asian great ape or orang-utan has been sequenced — specifically a draft assembly of a Sumatran female individual and short-read sequence data from five further Sumatran and five Bor...
-
Article
Erratum: A burst of segmental duplications in the genome of the African great ape ancestor
Nature 457, 877–881 (2009) In this Letter, Lynne V. Nazareth, Donna M. Muzny and Richard A. Gibbs were inadvertently omitted from the author list.
-
Article
A burst of segmental duplications in the genome of the African great ape ancestor
With four primate genome sequences now available — macaque, orang-utan, chimpanzee and human — it has become possible to construct a comparative segmental duplication map of four primate genomes. This has now ...
-
Article
Generation and annotation of the DNA sequences of human chromosomes 2 and 4
Human chromosome 2 is unique to the human lineage in being the product of a head-to-head fusion of two intermediate-sized ancestral chromosomes. Chromosome 4 has received attention primarily related to the sea...
-
Article
The DNA sequence of human chromosome 7
Human chromosome 7 has historically received prominent attention in the human genetics community, primarily related to the search for the cystic fibrosis gene and the frequent cytogenetic changes associated wi...
