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Open AccessEnzymatic chemonucleolysis for lumbar disc herniation—an assessment of historical and contemporary efficacy and safety: a systematic review and meta-analysis
Lumbar disc herniation (LDH) is often managed surgically. Enzymatic chemonucleolysis emerged as a non-surgical alternative. This systematic review and meta-analysis aims to assess the efficacy and safety of ch...
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Clinical effectiveness of reduction and fusion versus in situ fusion in the management of degenerative lumbar spondylolisthesis: a systematic review and meta-analysis
To compare the clinical effectiveness of reduction and fusion with in situ fusion in the management of patients with degenerative lumbar spondylolisthesis (DLS).
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Open AccessISSLS PRIZE in Basic Science 2024: superiority of nucleus pulposus cell- versus mesenchymal stromal cell-derived extracellular vesicles in attenuating disc degeneration and alleviating pain
To investigate the therapeutic potential of extracellular vesicles (EVs) derived from human nucleus pulposus cells (NPCs), with a specific emphasis on Tie2-enhanced NPCs, compared to EVs derived from human bon...
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Interventional treatments for low back pain due to sacroiliac joint dysfunction: a systematic review of the literature
This systematic review aimed to report the current evidence in the literature about the efficacy of interventional treatments in the management of low back pain (LBP) due to sacroiliac joint dysfunction.
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Open AccessMassive foreign body reaction and osteolysis following primary anterior cruciate ligament reconstruction with the ligament augmentation and reconstruction system (LARS): a case report with histopathological and physicochemical analysis
Autologous hamstrings and patellar tendon have historically been considered the gold standard grafts for anterior cruciate ligament reconstruction (ACLR). In the last decades, the utilization of synthetic graf...
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Open AccessThe role of the orthopaedic surgeon in the COVID-19 era: cautions and perspectives
The current coronavirus disease 2019 (COVID-19) pandemic has revolutionized global healthcare in an unprecedented way and with unimaginable repercussions. Resource reallocation, socioeconomic confinement and r...
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Reference Work Entry In depth
Bioceramics and Biocomposites in Spine Surgery
Spinal arthrodesis is an essential procedure in spine surgery which is performed to fuse two or more vertebrae. Success rates and outcomes strictly depend on substrates used to achieve a solid bony fusion of t...
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Living Reference Work Entry In depth
Bioceramics and Biocomposites in Spine Surgery
Spinal arthrodesis is an essential procedure in spine surgery which is performed to fuse two or more vertebrae. Success rates and outcomes strictly depend on substrates used to achieve a solid bony fusion of t...
