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    Article

    miR-486-5p diagnosed atrial fibrillation, predicted the risk of left atrial fibrosis, and regulated angiotensin II-induced cardiac fibrosis via modulating PI3K/Akt signaling through targeting FOXO1

    This study focused on miR-486-5p in atrial fibrillation (AF) evaluating its clinical significance and revealing its regulatory mechanism in cardiac fibroblasts, aiming to explore a novel biomarker for AF. The ...

    Fang Zhang, Lu Geng, **g Zhang, Siliang Han in Molecular and Cellular Biochemistry (2024)

  2. Article

    Open Access

    Transcription factor Sp1 transcriptionally enhances GSDME expression for pyroptosis

    Gasdermin-E (GSDME), the executioner of pyroptosis when cleaved by caspase 3, plays a crucial role in tumor defense and the response to chemotherapy drugs in cells. So far, there are poorly known mechanisms fo...

    Jiasong Pan, Yuanyuan Li, Wenqing Gao, Qizhou Jiang, Lu Geng in Cell Death & Disease (2024)

  3. Article

    Open Access

    MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

    Parkinson’s disease (PD), one of the most devastating neurodegenerative brain disorders, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and deposits of α-synuclei...

    Lu Geng, Wenqing Gao, Hexige Saiyin, Yuanyuan Li, Yu Zeng in Molecular Neurodegeneration (2023)

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    Article

    Development of a magnetic separation immunoassay with high sensitivity and time-saving for detecting aflatoxin B1 in agricultural crops using nanobody

    Detection methods with high sensitivity and short assay time are urgently required for quantitative analysis of small-molecule hazardous substances in food monitoring. In this work, a new anti-aflatoxin B1 (AFB1)...

    **nyang Wang, Wentao Liu, Hu Zuo, Weili Shen in European Food Research and Technology (2023)

  5. No Access

    Chapter and Conference Paper

    The Construction of Story-Telling Illustration in Tea Packaging Design

    With the improvement of the economic level and the prosperity of the commodity market, consumers’ demand for commodities is not only at the material level. The packaging design of the story illustration has st...

    Ren Long, Lu Geng, Chenyue Sun in Advances in Industrial Design (2020)

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    Article

    Data-Driven User Complaint Prediction for Mobile Access Networks

    In this paper, we present a user-complaint prediction system for mobile access networks based on network monitoring data. By applying machine-learning models, the proposed system can relate user complaints to ...

    Huimin Pan, Sheng Zhou, Yunjian Jia in Journal of Communications and Information … (2018)

  7. No Access

    Article

    Molecular marker of high glycyrrhizic acid content based on the SNPs of liquorice IPT gene

    Previous studies found that cytokinins (CTKs) are able to significantly promote glycyrrhizic acid (GA) accumulation. This study analyzed the correlation between the contents of GA and CTKs in 98 one-year-old l...

    Yanpeng Li, Lu Geng, **g Chen, Ying Huang, **g Qiao, Guangxi Ren in 3 Biotech (2018)

  8. No Access

    Chapter and Conference Paper

    Preparation and Performance Investigation of the Flexible Pressure Sensor

    Recently, the flexible pressure sensor has attracted significant attentions as its high performance and wide applications, including wearable electronics, environmental monitoring device, and human-machine int...

    Qingbin Zhai, Lixin Mo, Wei Yang in Advanced Graphic Communications, Packaging… (2016)