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  1. No Access

    Article

    Mzb1 Attenuates Atherosclerotic Plaque Vulnerability in ApoE-/- Mice by Alleviating Apoptosis and Modulating Mitochondrial Function

    In this study, we investigated the protective role of Mzb1 in atherosclerotic plaque vulnerability. To explore the impact of Mzb1, we analyzed Mzb1 expression, assessed apoptosis, and evaluated mitochondrial f...

    Guanglang Zhu, Yang Li, Hongxia Gao, Xu Li… in Journal of Cardiovascular Translational Re… (2024)

  2. Article

    Open Access

    Excimer laser ablation combined with drug-coated balloon versus drug-coated balloon in the treatment of de novo atherosclerotic lesions in lower extremities (ELABORATE): study protocol for a real-world clinical trial

    The efficacy and validity of excimer laser ablation (ELA) in the in-stent restenosis (ISR) has been confirmed. However, its application in de novo atherosclerotic lesions of lower extremity artery disease (LEA...

    **aolang Jiang, Longhua Fan, Bin Chen, Junhao Jiang… in BMC Cardiovascular Disorders (2022)

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  3. No Access

    Article

    Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy

    Defective autophagy in vascular smooth muscle cells (VSMCs) in response to oxidative stress can lead to cellular apoptosis and plaque instability. Previous studies have revealed that the circadian clock system...

    Zhenyu Guo, Baixue Yu, Xu Li, **aohu Yang, Chen Wang… in Journal of Molecular Histology (2021)