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  1. Article

    Open Access

    High-resolution spatiotemporal map**: a comprehensive view of eukaryotic cell cycle proteome dynamics

    **g Zou, Ziran Qin, Long Zhang in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    PARP1-DNA co-condensation: the driver of broken DNA repair

    DNA double-strand break (DSB) sites that prevent the disjunction of broken DNA ends are formed through poly (ADP-ribose) (PAR) polymerase 1 (PARP1)-DNA co-...

    **ang Wei, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2024)

  3. No Access

    Article

    The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer

    Gastric cancer (GC) is one of the most leading cause of malignancies. However, the molecular mechanisms underlying stomach carcinogenesis remain incompletely understood. Dysregulated genetic and epigenetic alt...

    Mengyu **e, Long Zhang, Linyu Han, Linying Huang, Yizhou Huang, Ming Yang in Oncogene (2023)

  4. Article

    Open Access

    Activated STING: an ion channel to trigger non-interferon-related functions

    Zhengyu Gao, Bin Wang, Long Zhang in Signal Transduction and Targeted Therapy (2023)

  5. Article

    Open Access

    Ras homolog family member J (RHOJ): a key regulator of chemoresistance associated with epithelial-mesenchymal transition

    Sijia Liu, Jiang Ren, Long Zhang in Signal Transduction and Targeted Therapy (2023)

  6. Article

    Open Access

    Deciphering dynamic changes of the aging transcriptome with COVID-19 progression and convalescence in the human blood

    Ran Li, **g Zou, Dongling Pei, Ting Pan in Signal Transduction and Targeted Therapy (2023)

  7. Article

    Open Access

    The loss of epigenetic information: not only consequences but a cause of mammalian aging

    Chen Pan, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2023)

  8. Article

    Open Access

    Motile cilia and microvillar: accomplices of SARS-CoV-2 in penetrating mucus barrier and infecting airway epithelium

    Peng Su, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2023)

  9. Article

    Open Access

    The fungal mycobiome: a new hallmark of cancer revealed by pan-cancer analyses

    Zhi Zong, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2023)

  10. Article

    Open Access

    Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions

    The global coronavirus disease 2019 (COVID-19) pandemic is currently ongoing. It is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A high proportion of COVID-19 patients exhibit gastro...

    Bin Wang, Lei Zhang, Yongqiang Wang, Tong Dai in Signal Transduction and Targeted Therapy (2022)

  11. Article

    Open Access

    SARS-CoV-2 Omicron variant: recent progress and future perspectives

    Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of which is the Omicron variant (...

    Yao Fan, **ang Li, Lei Zhang, Shu Wan in Signal Transduction and Targeted Therapy (2022)

  12. Article

    Open Access

    Novel pyroptosis-independent functions of gasdermins

    Ziran Qin, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2022)

  13. Article

    Open Access

    STING, a critical contributor to SARS-CoV-2 immunopathology

    Heyu Li, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2022)

  14. Article

    Open Access

    The way of SARS-CoV-2 vaccine development: success and challenges

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). To halt the pandemic, multiple SARS-CoV-2 vaccines have been developed and several ha...

    Yetian Dong, Tong Dai, Bin Wang, Lei Zhang in Signal Transduction and Targeted Therapy (2021)

  15. Article

    Open Access

    cGAS-like receptors: new RNA sensors in Drosophila

    Yao Fan, Long Zhang, Fangfang Zhou in Signal Transduction and Targeted Therapy (2021)

  16. Article

    Open Access

    Liquid–liquid phase separation in human health and diseases

    Emerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless organelles in eukaryotic cells (also known as biomole...

    Bin Wang, Lei Zhang, Tong Dai, Ziran Qin in Signal Transduction and Targeted Therapy (2021)

  17. Article

    Open Access

    Cancer Environment Immunotherapy: targeting TGF-β finds its way towards tissue healing and vasculature remodeling

    Ke **, Fangfang Zhou, Long Zhang in Signal Transduction and Targeted Therapy (2021)

  18. Article

    Open Access

    A systematic review of SARS-CoV-2 vaccine candidates

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that is highly pathogenic and has caused the recent worldwide pandemic officially named coronavirus disease (COVID-19). Current...

    Yetian Dong, Tong Dai, Yujun Wei, Long Zhang in Signal Transduction and Targeted Therapy (2020)

  19. Article

    Open Access

    GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies

    Cancer cells are usually characterized by hyperactive glucose metabolism, which can often lead to glucose scarcity; thus, alternative pathways to rewire cancer metabolism are required. Here, we demonstrated th...

    Weixing Dai, Ye Xu, Shaobo Mo, Qingguo Li in Signal Transduction and Targeted Therapy (2020)

  20. Article

    Open Access

    An effective platform for cancer immunotherapy: pooled knockin targeting for genome engineering

    Ke **, Long Zhang, Fangfang Zhou in Signal Transduction and Targeted Therapy (2020)

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