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The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood
Follicular regulatory T cells control humoral immune responses, but how these cells are in turn controlled has been unclear. Sharpe and colleagues demonstrate that signaling via PD-1 regulates number and funct...
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Article
Tumor-specific killer cells in paraneoplastic cerebellar degeneration
Models for immune-mediated tumor regression in mice have defined an essential role for cytotoxic T lymphocytes (CTLs); however, naturally occurring tumor immunity in humans is poorly understood ...