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Article
Utilizing metagenomic next-generation sequencing for pathogen detection and diagnosis in lower respiratory tract infections in real-world clinical practice
Infectious etiologies of lower respiratory tract infections (LRTIs) by the conventional microbiology tests (CMTs) can be challenging. Metagenomic next-generation sequencing (mNGS) has great potential in clinic...
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Article
Open AccessPhase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer
EGFR exon 20 insertion (20ins)-positive non-small-cell lung cancer (NSCLC) is an uncommon disease with limited therapeutic options and dismal prognosis. Here we report the activity, tolerability, potential mec...
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Article
Advances in studies on transcription factors in regulation of secondary metabolites in Chinese medicinal plants
The active ingredients of many Chinese medicinal plants are secondary metabolites, which exhibit pharmaceutical value. In the metabolism process of secondary metabolites, transcription factors play important r...
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Article
Reversing resistance to immune checkpoint inhibitor by adding recombinant human adenovirus type 5 in a patient with small cell lung cancer with promoted immune infiltration: a case report
Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Since immune checkpoint inhibitors (ICIs) have had significant benefits in SCLC, studying and overcoming the mechanisms of ICI res...
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Article
Stable and novel QTL identification and new insights into the genetic networks affecting seed fiber traits in Brassica napus
QTL map** for fiber-related traits and elucidation of a stable and novel QTL affecting seed lignin content, cellulose content and seed oil content.
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Article
On Weakly \(\mathcal {M}\) -Supplemented Subgroups and the \({\mathcal {F}}\) -Hypercentre of Finite Groups
A subgroup H of a finite group G is said to be weakly \(\mathcal {M}\) M
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Article
Open AccessThe initial deficiency of protein processing and flavonoids biosynthesis were the main mechanisms for the male sterility induced by SX-1 in Brassica napus
Rapeseed (Brassica napus) is an important oil seed crop in the Brassicaceae family. Chemical induced male sterility (CIMS) is one of the widely used method to produce the hybrids in B. napus. Identification of th...
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Article
On the supersoluble hypercentre of a finite group
We give some sufficient conditions for a normal p-subgroup P of a finite group G to have every G-chief factor below it cyclic. The S-permutability of some p-subgroups of
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Article
Some Criteria for p-Supersolvability of a Finite Group
A subgroup H of a finite group G is said to be S-semipermutable in G if H permutes with all Sylow q-subgroups of G for the primes q not dividing the order of H. Some criteria for p-supersolvability of a finite gr...
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Article
Open AccessIdentification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients
Although many of the recently approved genomically targeted therapies have improved outcomes for patients in non–small-cell lung cancer (NSCLC) with lung adenocarcinoma, little is known about the genomic alter...
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Article
Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung cancer and promotes cell invasion via epithelial-to-mesenchymal transition
Discoidin domain receptors (DDRs) are a novel class of receptor tyrosine kinases that respond to several collagens and facilitate cell adhesion. DDR1 is highly expressed in a variety of human cancers, and it i...
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Article
Studies on species diversity of Larix chinensis community ecotone
The communities of Larix chinensis and their ecotone in Qinling Mountains were investigated by sampling belt method. Species richness, Simpson diversity, Shannon-Weiner diversity, PIE and Pielou evenness indices ...
