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Article
Open AccessDUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad signaling pathway in lung adenocarcinoma
Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of cancer metastasis and drug resistance. The study aims to identify the genes that concurrently modulate EMT, metastasis and EGFR-TKI re...
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Article
Open AccessGWAS Combined with WGCNA of Transcriptome and Metabolome to Excavate Key Candidate Genes for Rice Anaerobic Germination
Direct seeding of rice is a lightweight and simple cultivation method, which can effectively promote rice production. Anaerobic germination tolerance is one of the main traits of rice adaptability to direct se...
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Article
Small Auxin Up RNA 56 (SAUR56) regulates heading date in rice
Heading date is a critical agronomic trait that determines crop yield. Although numerous genes associated with heading date have been identified in rice, the mechanisms involving Small Auxin Up RNA (SAUR) family ...
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Article
Characterization of GshAB of Tetragenococcus halophilus: a two-domain glutathione synthetase
The γ-glutamyl tripeptide glutathione (γ-Glu-Cys-Gly) is a low molecular thiol that acts as antioxidant in response to oxidative stress in eukaryotes and prokaryotes. γ-Glutamyl dipeptides including γ-Glu-Cys,...
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Article
Genome-wide association study reveals novel genetic loci involved in anaerobic germination tolerance in Indica rice
Increasing numbers of rice farmers are adopting methods of direct seeding in flooded paddy fields to save costs associated with labor and transplanting. Successful seedling establishment under anoxic condition...
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Article
Characterization of DinJ-YafQ toxin–antitoxin module in Tetragenococcus halophilus: activity, interplay, and evolution
Tetragenococcus halophilus is a moderately halophilic lactic acid bacterium widely used in high-salt food fermentation because of its co** ability under various stress conditions. Bacterial toxin–antitoxin (TA)...
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Article
Open AccessDynamic genome-wide association analysis and identification of candidate genes involved in anaerobic germination tolerance in rice
In Asian rice production, an increasing number of countries now choose the direct seeding mode because of rising costs, labour shortages and water shortages. The ability of rice seeds to undergo anaerobic germ...
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Article
Characterization of the two nonidentical ArgR regulators of Tetragenococcus halophilus and their regulatory effects on arginine metabolism
The halophilic lactic acid bacterium Tetragenococcus halophilus has been widely used in high-salinity fermentation processes of food. Previous studies have indicated that the catabolism of arginine may contribute...
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Article
Open AccessDynamic transcriptome and metabolome analyses of two types of rice during the seed germination and young seedling growth stages
Seed germination and young seedling growth are important agricultural traits for develo** populations of both irrigated and directly seeded rice. Previous studies have focused on the identification of QTLs. ...
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Article
Identification of a GntR family regulator BusRTha and its regulatory mechanism in the glycine betaine ABC transport system of Tetragenococcus halophilus
Glycine betaine is one of the most effective compatible solutes of the halophilic lactic acid bacterium Tetragenococcus halophilus, the transportation of which is essential for its survival under salinity stress ...
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Article
Integrating GWAS, QTL, map** and RNA-seq to identify candidate genes for seed vigor in rice (Oryza sativa L.)
Seed vigor is an important seed quality trait in rice (Oryza sativa L.) that profoundly affects seedling morphogenesis in different environments. Generally, highly vigorous seeds have many advantages in agricultu...
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Article
Open AccessIdentification of stable QTLs and candidate genes involved in anaerobic germination tolerance in rice via high-density genetic map** and RNA-Seq
Anaerobic germination tolerance is an important trait for direct-seeded rice varieties. Understanding the genetic basis of anaerobic germination is a key for breeding direct-seeded rice varieties.
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Article
Genome sequence and annotation of Sporolactobacillus pectinivorans GD201205 T, a lactic acid-producing bacterium
The novel species Sporolactobacillus pectinivorans GD201205T can produce lactic acid and aromatic compounds such as isoamyl acetate and phenethyl acetate. To characterize this strain, we sequenced the whole genom...
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Spatial Skills Framework for Young Engineers
is a spatially demanding field. Yet, unlike previously held assumptions, recent research reveals that spatial ability is not innate, but that through experience, education, and intervention, people of all a...
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Article
Diversity and dynamics stability of bacterial community in traditional solid-state fermentation of Qishan vinegar
Qishan vinegar is a typical Chinese fermented cereal product that is prepared using traditional solid-state fermentation (SSF) techniques. The final qualities of the vinegar produced are closely related to the...
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Article
Genomic analysis of type strain Paenibacillus aceti L14T, a highly efficient producer of pyrazines
Paenibacillus aceti L14T (CGMCC 1.15420 = JCM 31170) is a novel species isolated from the solid-state acetic acid fermentation culture of traditional Chinese vinegar. The strain is able t...
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Article
A salt-induced butA gene of Tetragenococcus halophilus confers salt tolerance to Escherichia coli by heterologous expression of its dual copies
Accumulating glycine betaine through the ButA transport system from an exogenous supply is a survival strategy employed by Tetragenococcus halophilus, a moderate halophilic lactic acid bacterium with crucial role...
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Article
Bacterial dynamics and metabolite changes in solid-state acetic acid fermentation of Shanxi aged vinegar
Solid-state acetic acid fermentation (AAF), a natural or semi-controlled fermentation process driven by reproducible microbial communities, is an important technique to produce traditional Chinese cereal vineg...
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Article
Characterization of activity and microbial diversity of typical types of Daqu for traditional Chinese vinegar
Daqu is a fermentation starter used in traditional Chinese vinegar production and determines the quality of the final vinegar products. In this study, the activity and microbial diversity of three typical type...
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Article
Comparative transcriptomic analysis reveals novel genes and regulatory mechanisms of Tetragenococcus halophilus in response to salt stress
Tetragenococcus halophilus, a moderately halophilic Gram-positive bacterium, was isolated from Chinese style soy sauce. This species is a valuable resource for investigating salt tolerance mechan...
