5 Result(s)
within
Lixin Du
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessPreparation, characterization and in vivo pharmacokinetic study of ginsenoside Rb1-PLGA nanoparticles
This study aimed to construct a Ginsenoside Rb1-PLGA nano drug delivery system, optimize its preparation process, characterize and evaluate the resulting Ginsenoside Rb1-PLGA Nanoparticles (GRb1@PLGA@NPs). GRb...
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Article
Open AccessGenome-wide detection of CNVs in Chinese indigenous sheep with different types of tails using ovine high-density 600K SNP arrays
Chinese indigenous sheep can be classified into three types based on tail morphology: fat-tailed, fat-rumped, and thin-tailed sheep, of which the typical breeds are large-tailed Han sheep, Altay sheep, and Tib...
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Article
Open AccessGenome-wide analysis reveals adaptation to high altitudes in Tibetan sheep
Tibetan sheep have lived on the Tibetan Plateau for thousands of years; however, the process and consequences of adaptation to this extreme environment have not been elucidated for important livestock such as ...
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Article
Open AccessRosa26-targeted sheep gene knock-in via CRISPR-Cas9 system
Recent advances in our ability to design DNA binding factors with specificity for desired sequences have resulted in a revolution in genetic engineering, enabling directed changes to the genome to be made rela...
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Article
Open AccessDNA methylation Landscape of body size variation in sheep
Sub-populations of Chinese Mongolian sheep exhibit significant variance in body mass. In the present study, we sequenced the whole genome DNA methylation in these breeds to detect whether DNA methylation plays...
