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  1. Article

    Open Access

    CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels

    Genetic testing is crucial for precision cancer medicine. However, detecting multiple same-site insertions or deletions (indels) is challenging. Here, we introduce CoHIT (Cas12a-based One-for-all High-speed Is...

    Yin Liu, **nyi Liu, Dongyi Wei, Lu Dang, **aoran Xu in Nature Communications (2024)

  2. Article

    Open Access

    Systolic blood pressure status modifies the associations between the triglyceride-glucose index and incident cardiovascular disease: a national cohort study in China

    The triglyceride-glucose (TyG) index and blood pressure (BP) are correlated and serve as risk factors for cardiovascular disease (CVD). The potential impact of BP status on the association between the TyG inde...

    Weida Qiu, An** Cai, Liwen Li, Yingqing Feng in Cardiovascular Diabetology (2024)

  3. Article

    Open Access

    Segregation of morphogenetic regulatory function of Shox2 from its cell fate guardian role in sinoatrial node development

    Shox2 plays a vital role in the morphogenesis and physiological function of the sinoatrial node (SAN), the primary cardiac pacemaker, manifested by the formation of a hypoplastic SAN and failed differentiation of...

    Hua Li, Qinghuang Tang, Tianfang Yang, Zhengsen Wang, Dainan Li in Communications Biology (2024)

  4. Article

    Open Access

    The association between TyG and all-cause/non-cardiovascular mortality in general patients with type 2 diabetes mellitus is modified by age: results from the cohort study of NHANES 1999–2018

    The prognostic value of triglyceride-glucose (TyG) index in general type 2 diabetes mellitus (T2DM) patients is still unclear. Therefore, we aimed to determine the associations between TyG and all-cause/cause-...

    Younan Yao, Bo Wang, Tian Geng, Jiyan Chen, Wan Chen in Cardiovascular Diabetology (2024)

  5. Article

    Open Access

    NF-κB RelA is a cell-intrinsic metabolic checkpoint restricting glycolysis

    An intrinsic link between metabolism and function in immune cells, and in particular macrophages, has been well established recently. However, the molecular mechanisms controlling the metabolic switch in these...

    Liwen Li, Lei Han, Zhaoxia Qu in Cell & Bioscience (2024)

  6. Article

    Open Access

    Diabetes mellitus status modifies the association between N-terminal B-type natriuretic peptide and all-cause mortality risk in ischemic heart failure: a prospective cohort study

    N-terminal B-type natriuretic peptide (NT-proBNP) discriminates mortality risk in diabetes mellitus (DM) and in heart failure (HF) populations. Whether DM status modifies the association between NT-proBNP and ...

    Weida Qiu, An** Cai, **aoju **ao, Zhi** Gao in Diabetology & Metabolic Syndrome (2023)

  7. No Access

    Chapter and Conference Paper

    Analysis on Factors Affecting Financial Industry Annual Profit Based on Linear Regression Model

    Financial development has always been an essential part of the national economy. How to achieve financial development and continuous improvement has been a hot topic of research in China’s finance field. With ...

    Liwen Li, Yanbo Wang, Kexin Wei in Proceedings of the 2nd International Confe… (2023)

  8. Article

    Open Access

    A simple nomogram for assessing the risk of IgA vasculitis nephritis in IgA vasculitis Asian pediatric patients

    A nomogram for assessing the risk of IgA vasculitis nephritis (originally termed Henoch–Schönlein purpura nephritis, HSPN) in IgA vasculitis (originally termed Henoch–Schönlein purpura, HSP) pediatric patients...

    Yuna Bi, Wei Quan, Wei Hao, Rui Sun, Liwen Li, Chun** Jiang in Scientific Reports (2022)

  9. Article

    Open Access

    The clinical significance of BRAFV600E mutations in pediatric papillary thyroid carcinomas

    This study aimed to review the clinical significance of BRAFV600E mutations in pediatric papillary thyroid carcinoma (PTC). From 2018 to 2021, 392 pediatric thyroid operations were performed in the first affil...

    Yangsen Li, Yuanyuan Wang, Liwen Li, **nguang Qiu in Scientific Reports (2022)

  10. No Access

    Article

    Left atrial remodeling and the prognostic value of feature tracking derived left atrial strain in patients with light-chain amyloidosis: a cardiovascular magnetic resonance study

    Systemic light-chain (AL) amyloidosis is characterized by the aggregation of misfolded immunoglobulin light chain, predominantly infiltrating in the heart, including left atrium (LA). LA remodeling, such as in...

    Zekun Tan, Yuelong Yang, **nyi Wu, Sheng Li in The International Journal of Cardiovascula… (2022)

  11. Article

    Open Access

    The role m6A RNA methylation is CNS development and glioma pathogenesis

    Epigenetic abnormalities play a crucial role in many tumors, including glioma. RNA methylation occurs as an epigenetic modification similar to DNA methylation and histone modification. m6A methylation is the most...

    Ting Pan, Fan Wu, Liwen Li, Shiyan Wu, Fang Zhou, ** Zhang in Molecular Brain (2021)

  12. Article

    Open Access

    The association of lipoprotein(a) and intraplaque neovascularization in patients with carotid stenosis: a retrospective study

    Lipoprotein(a) is genetically determined and increasingly recognized as a major risk factor for arteriosclerotic cardiovascular disease. We examined whether plasma lipoprotein(a) concentrations were associated...

    Shuang **a, Weida Qiu, An** Cai, Bo Kong, Lan Xu in BMC Cardiovascular Disorders (2021)

  13. Article

    Open Access

    Genetic analysis using targeted next-generation sequencing of sporadic Chinese patients with idiopathic dilated cardiomyopathy

    Inherited dilated cardiomyopathy (DCM) contributes to approximately 25% of idiopathic DCM cases, and the proportion is even higher in familial DCM patients. Most studies have focused on familial DCM, whereas t...

    Mingmin Li, Shuang **a, Lan Xu, Hong Tan, Junqing Yang in Journal of Translational Medicine (2021)

  14. No Access

    Article

    Effect of Graves’ disease on the prognosis of differentiated thyroid carcinoma: a meta-analysis

    Several studies have reported different findings on the prognosis of differentiated thyroid carcinoma combined with Graves’ disease. To assess the effect of Graves’ disease on differentiated thyroid carcinoma,...

    Yang Song, Lijun Fu, Pu Wang, Ning Sun, **nguang Qiu, Jianhua Li in Endocrine (2020)

  15. No Access

    Book and Conference Proceedings

    Asian Research on English for Specific Purposes

    Proceedings of the First Symposium on Asia English for Specific Purposes, 2017

    Youzhong Sun, Liwen Li, Hong Cai (2020)

  16. No Access

    Chapter and Conference Paper

    Application of the UAV Technology in the Topographic Map Survey

    The UAV aerial survey technology is a new aerial remote sensing technology developed after the satellite remote sensing and the large aircraft remote sensing. It has been widely used in the emergency map** s...

    **nglin Jiang, Jiangtao Liu, Hongbin Zhen, Liwen Li, Zhaogang Xu in Frontier Computing (2020)

  17. Article

    Open Access

    Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

    Most cancers are resistant to anti-PD-1/PD-L1 and chemotherapy. Herein we identify PDLIM2 as a tumor suppressor particularly important for lung cancer therapeutic responses. While PDLIM2 is epigenetically repr...

    Fan Sun, Liwen Li, Pengrong Yan, **gjiao Zhou, Steven D. Shapiro in Nature Communications (2019)

  18. Article

    Open Access

    Therapeutic effect of vasoactive intestinal peptide on form-deprived amblyopic kittens

    Exploring the role of vasoactive intestinal peptide (VIP) in the lateral geniculate body (LGBd) in visual development and studying the therapeutic effect of VIP on amblyopic kittens.

    Bo Li, Yunchun Zou, Liwen Li, Hongwei Deng, Wei Mi, **ng Wang in BMC Ophthalmology (2019)

  19. No Access

    Article

    The comparison of short-term prognostic value of T1 map** with feature tracking by cardiovascular magnetic resonance in patients with severe dilated cardiomyopathy

    To evaluate and compare the prognostic value of T1 map** with feature tracking cardiovascular magnetic resonance (FT-CMR) imaging in patients with severe dilated cardiomyopathy (DCM) during short-term follow...

    Rui Chen, **g**g Wang, Zhicheng Du in The International Journal of Cardiovascula… (2019)

  20. No Access

    Article

    A Mixed Methods Evaluation of College English Writing: A Case Study in China

    China’s recent curriculum reform of English as a foreign language programs has shifted toward an integration of language abilities and transferable skills such as intercultural skills. This study is part of an...

    Hong**g Liao, Liwen Li in The Asia-Pacific Education Researcher (2017)

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