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Article
Open AccessRetinal sensitivity changes in early/intermediate AMD: a systematic review and meta-analysis of visual field testing under mesopic and scotopic lighting
Visual fields under mesopic and scotopic lighting are increasingly being used for macular functional assessment. This review evaluates its statistical significance and clinical relevance, and the optimal testi...
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Article
Open AccessMultispectral pattern recognition measures change in drusen area in age-related macular degeneration with high congruency to expert graders
Drusen are a hallmark lesion of age-related macular degeneration (AMD) and changes in their area and/or volume are strongly associated with disease progression. Assessment of longitudinal change in drusen size...
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Article
Open AccessModelling normal age-related changes in individual retinal layers using location-specific OCT analysis
Current descriptions of retinal thickness across normal age cohorts are mostly limited to global analyses, thus overlooking spatial variation across the retina and limiting spatial analyses of retinal and opti...
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Article
Open AccessNormal aging changes in the choroidal angioarchitecture of the macula
The choroidal vascularity index (CVI) has been shown to be sensitive in detecting changes in choroidal angioarchitecture in a range of ocular diseases. However, changes in CVI in association with normal physio...
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Article
Open AccessContrast sensitivity isocontours of the central visual field
Standard automated perimetry (SAP), the most common form of perimetry used in clinical practice, is associated with high test variability, impacting clinical decision making and efficiency. Contrast sensitivit...