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  1. No Access

    Article

    Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy

    The most widely used fluorophore in glioma-resection surgery, 5-aminolevulinic acid (5-ALA), is thought to cause the selective accumulation of fluorescent protoporphyrin IX (PpIX) in tumour cells. Here we show...

    Mustafa Nasir-Moin, Lisa Irina Wadiura, Vlad Sacalean… in Nature Biomedical Engineering (2024)

  2. No Access

    Article

    Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging

    Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brai...

    Todd Hollon, Cheng Jiang, Asadur Chowdury, Mustafa Nasir-Moin… in Nature Medicine (2023)