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  1. No Access

    Article

    A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy

    Autophagy is a conserved degradation process that occurs in all eukaryotic cells and its dysfunction has been associated with various diseases including cancer. While a number of large-scale attempts have rece...

    Imke Tiessen, Marie H. Abildgaard, Michal Lubas, Helene M. Gylling in Oncogene (2019)

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    Open Access

    Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1

    Cancer cells utilize lysosomes for invasion and metastasis. Myeloid Zinc Finger1 (MZF1) is an ErbB2-responsive transcription factor that promotes invasion of breast cancer cells via upregulation of lysosomal c...

    Siri Amanda Tvingsholm, Malene Bredahl Hansen in Oncogenesis (2018)

  3. Article

    Open Access

    MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells

    MicroRNAs (miRNAs) are well recognized as gene regulators and have been implicated in the regulation of development as well as human diseases. miR-143 is located at a fragile site on chromosome 5 frequently de...

    Lea H Gregersen, Anders Jacobsen, Lisa B Frankel, Jiayu Wen, Anders Krogh in BMC Cancer (2012)

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    Article

    Protein Kinase C α is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells

    Development of resistance to antiestrogen treatment in breast cancer patients is a serious therapeutic problem. The molecular mechanisms contributing to resistance are currently unclear; however it is known th...

    Lisa B. Frankel, Anne E. Lykkesfeldt in Breast Cancer Research and Treatment (2007)