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Article
Non-structural proteins of bovine viral diarrhea virus
Bovine viral diarrhea virus (BVDV) belongs to the family Flaviviridae genus pestivirus. The viral genome is a single-stranded, positive-sense RNA that encodes four structural proteins (i.e., C, Erns, E1, and E...
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Article
Open AccessBrucella melitensis UGPase inhibits the activation of NF-κB by modulating the ubiquitination of NEMO
UTP-glucose-1-phosphoryl transferase (UGPase) catalyzes the synthesis of UDP-glucose, which is essential for generating the glycogen needed for the synthesis of bacterial lipopolysaccharide (LPS) and capsular ...
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Article
Open AccessHuman cells are permissive for the productive infection of porcine circovirus type 2 in vitro
Porcine circovirus 2 (PCV2) is the main pathogen of porcine circovirus diseases and porcine circovirus-associated diseases, which are widespread in swine-producing countries. However, there is controversy rega...
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Article
Open AccessImmunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice
Vaccination is considered as an effective and economical way to against PCV2 infection. However, some of commercial available vaccines are based on inactivated viruses, while the others are based on purified p...
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Article
Live Cell Reporter Systems for Positive-Sense Single Strand RNA Viruses
Cell-based reporter systems have facilitated studies of viral replication and pathogenesis, virus detection, and drug susceptibility testing. There are three types of cell-based reporter systems that express c...
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Article
Analysis of molecular variation in porcine reproductive and respiratory syndrome virus in China between 2007 and 2012
In the present study, 89 porcine reproductive and respiratory syndrome virus (PRRSV) isolates in China during 2007 to 2012 were randomly selected from the GenBank genetic sequence database. Evolutionary charac...
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Article
Open AccessMolecular characterization of a Chinese variant of the Flury-LEP strain
The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was 11 924 nu...
