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  1. Article

    Open Access

    Exosomes derived from BMSCs enhance diabetic wound healing through circ-Snhg11 delivery

    Exosomes (Exos) generated from bone mesenchymal stem cells (BMSCs) are elucidated to enhance cutaneous wound healing in mice models of diabetes mellitus (DM). While underlying mechanisms remain unknown.

    Tao Tang, Linyi Chen, Ming Zhang, Chuang Wang in Diabetology & Metabolic Syndrome (2024)

  2. Article

    Open Access

    What Causes the Discrepancy in SARS-CoV-2 Vaccine Between Parental Hesitancy for Themselves and for Their Children During Lockdown Period?

    Parents are usually the decision-makers for vaccinations of children. Therefore, it is important to understand parental beliefs and attitudes toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

    Tianshuo Zhao, Chao Wang, Sihui Zhang in Journal of Epidemiology and Global Health (2023)

  3. No Access

    Article

    Combined application of biochar and magnesium fertilizer effectively improved the soil environment and the tea quality in southern strongly acidic tea garden

    Soil acidification and magnesium (Mg) deficiency are common in tea gardens in southern China. The application of Mg fertilizer and biochar combined with fertilizer is considered as one of the effective agronom...

    Hao Guo, Linyi Chen, Yixiang Wang, Qinghua Li, Zhigang Yi in Journal of Soils and Sediments (2023)

  4. Article

    Open Access

    Timely expression of PGAM5 and its cleavage control mitochondrial homeostasis during neurite re-growth after traumatic brain injury

    Patients suffered from severe traumatic brain injury (TBI) have twice the risk of develo** into neurodegenerative diseases later in their life. Thus, early intervention is needed not only to treat TBI but al...

    Min-Zong Liang, Ting-Hsuan Lu, Linyi Chen in Cell & Bioscience (2023)

  5. No Access

    Article

    Ketamine promotes breast tumor growth in a mouse breast tumor model involving with high expression of miR-27b-3p and EGFR

    Non-medical use of ketamine as an adulterant to ecstasy is more prevalent than amphetamine in Taiwan. Ketamine’s effect on immunosuppression might play some functional role in tumor growth, while it is still c...

    Li-Kuei Chen, Chien-Hung Shih, Shiou-Sheng Chen, Zi-Xuan Huang in Investigational New Drugs (2022)

  6. No Access

    Chapter and Conference Paper

    Research Review of Color Appearance Phenomenon and Models

    Color appearance models are of significance for researching in the area of color science, especially the cross-media color reproduction and transfer of images. These models can be used to solve series of probl...

    Qifeng Chen, Xue Li, Linyi Chen in Advanced Graphic Communication, Printing a… (2020)

  7. No Access

    Chapter and Conference Paper

    Research on Improving Display Effect of Micro-lens 3D Printing

    Micro-lens 3D printing technology, which can achieve naked-eye 3D effect in 360° perspective without any special observation equipment or skills, has gradually become a research hotspot in the field of 3D prin...

    Linyi Chen, Guangxue Chen in Advanced Graphic Communication, Printing a… (2020)

  8. Article

    Open Access

    Current progress of mitochondrial transplantation that promotes neuronal regeneration

    Mitochondria are the major source of intracellular adenosine triphosphate (ATP) and play an essential role in a plethora of physiological functions, including the regulation of metabolism and the maintenance o...

    Chu-Yuan Chang, Min-Zong Liang, Linyi Chen in Translational Neurodegeneration (2019)

  9. Article

    Open Access

    ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma

    Decreased expression of metallothionein-1 (MT-1) is associated with a poor prognosis in hepatocellular carcinoma (HCC). Here, we found that MT-1 expression was suppressed by 14-3-3ε, and MT-1 overexpression ab...

    Yi-Ju Wu, Bor-Sheng Ko, Shu-Man Liang, Yi-Jhu Lu, Yee-Jee Jan in Cell Death & Disease (2019)

  10. No Access

    Chapter and Conference Paper

    Utilization of Smart Nanomaterials for Fruit Fresh Kee**

    This research reported the fresh-kee** effectivity of smart nanomaterials for bananas and kiwis. The fresh-kee** gas, 1-methylcyclopropene (1-MCP), was loaded in self-assembled nano microballoon of cyclode...

    Zuguang Shen, Guangxue Chen, Lin** Chen in Applied Sciences in Graphic Communication … (2018)

  11. Article

    Open Access

    Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels

    Resveratrol, a phytoalexin found in grapes and red wine, exhibits diverse pharmacological activities. However, relatively little is known about whether resveratrol modulates the ion channels in cortical neuron...

    Ya-Jean Wang, Ming-Huan Chan, Linyi Chen, Sheng-Nan Wu in Journal of Biomedical Science (2016)

  12. Article

    Open Access

    Divergent signaling pathways cooperatively regulate TGFβ induction of cysteine-rich protein 2 in vascular smooth muscle cells

    Vascular smooth muscle cells (VSMCs) of the arterial wall play a critical role in the development of occlusive vascular diseases. Cysteine-rich protein 2 (CRP2) is a VSMC-expressed LIM-only protein, which func...

    Meng-Ling Wu, Chung-Huang Chen, Yung-Tsang Lin in Cell Communication and Signaling (2014)

  13. Article

    Open Access

    The antagonism between MCT-1 and p53 affects the tumorigenic outcomes

    MCT-1 oncoprotein accelerates p53 protein degradation via a proteosome pathway. Synergistic promotion of the xenograft tumorigenicity has been demonstrated in circumstance of p53 loss alongside MCT-1 overexpre...

    Ravi Kasiappan, Hung-Ju Shih, Meng-Hsun Wu, ChikOn Choy, Tai-Du Lin in Molecular Cancer (2010)

  14. Article

    Open Access

    The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons

    SH2B1β is a signaling adaptor protein that has been shown to promote neuronal differentiation in PC12 cells and is necessary for the survival of sympathetic neurons. However, the mechanism by which SH2B1β may ...

    Wan-Chen Lu, Chien-Jen Chen, Hui-Chien Hsu, Hsin-Ling Hsu in Journal of Molecular Signaling (2010)