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Open AccessMetabolic score for insulin resistance (METS-IR) predicts all-cause and cardiovascular mortality in the general population: evidence from NHANES 2001–2018
The prevalence of obesity-associated insulin resistance (IR) is increasing along with the increase in obesity rates. In this study, we compared the predictive utility of four alternative indexes of IR [triglyc...
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Article
Open AccessDysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
Deposition of amyloid β, which is produced by amyloidogenic cleavage of APP by β- and γ-secretase, is one of the primary hallmarks of AD pathology. APP can also be processed by α- and γ-secretase sequentially,...
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Article
Resonance Analysis in a High-Rise Building: Combined Translational and Rotational Measurements
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Article
Open AccessSwim bladder-derived biomaterials: structures, compositions, properties, modifications, and biomedical applications
Animal-derived biomaterials have been extensively employed in clinical practice owing to their compositional and structural similarities with those of human tissues and organs, exhibiting good mechanical prope...
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Article
Open AccessA approach of gastric conduit via the anterior of pulmonary hilum route during minimally invasive McKeown esophagectomy
The gastric conduit is the most commonly used replacement organ for reconstruction after minimally invasive McKeown esophagectomy. Although the optimal route of gastric conduit remains controversial, the poste...
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Article
Open AccessPathogenesis of allergic diseases and implications for therapeutic interventions
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD), food allergy (FA), and eczema are systemic diseases caused by an impaired immune system. Accompanied by high rec...
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Article
Open AccessNuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation
Pluripotent stem cells hold great promise in regenerative medicine and developmental biology studies. Mitochondrial metabolites, including tricarboxylic acid (TCA) cycle intermediates, have been reported to pl...
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Article
Correction to: MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening
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Article
Open AccessPrenatal genetic diagnosis of tetrasomy 18p from maternal trisomy 18p: a case report
Tetrasomy 18p syndrome is a rare chromosomal disorder that is caused by the presence of isochromosome 18p. Most tetrasomy 18p cases are de novo cases and maternal origin of trisomy 18p is a rare condition. At ...
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Article
Open AccessTransport of intensity diffraction tomography with non-interferometric synthetic aperture for three-dimensional label-free microscopy
We present a new label-free three-dimensional (3D) microscopy technique, termed transport of intensity diffraction tomography with non-interferometric synthetic aperture (TIDT-NSA). Without resorting to interf...
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Article
Open AccessChip-integrated van der Waals PN heterojunction photodetector with low dark current and high responsivity
Two-dimensional materials are attractive for constructing high-performance photonic chip-integrated photodetectors because of their remarkable electronic and optical properties and dangling-bond-free surfaces....
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Article
Open AccessmiR-203, fine-tunning neuroinflammation by juggling different components of NF‐κB signaling
miR-203 was first indicated in maintaining skin homeostasis and innate immunity. Aberrant expression of miR-203 was found associated with pathological progressions of immune disorders, cancers, as well as neur...
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Article
Open AccessProteomic landscape subtype and clinical prognosis of patients with the cognitive impairment by Japanese encephalitis infection
Cognitive impairment is one of the primary sequelae affecting the quality of life of patients with Japanese encephalitis (JE). The clinical treatment is mainly focused on life support, lacking of targeted trea...
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Open AccessAcupuncture for cancer pain: an evidence-based clinical practice guideline
This study aims to develop an evidence-based clinical practice guideline of acupuncture in the treatment of patients with moderate and severe cancer pain.
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Open AccessSmart computational light microscopes (SCLMs) of smart computational imaging laboratory (SCILab)
Computational microscopy, as a subfield of computational imaging, combines optical manipulation and image algorithmic reconstruction to recover multi-dimensional microscopic images or information of micro-obje...
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Article
Open AccessPerformance evaluation of medical service for breast cancer patients based on diagnosis related groups
To evaluate the performance of medical service for patients with breast cancer in Henan Province, China, using diagnosis related groups (DRGs) indicators and to provide data to inform practices and policies fo...
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Article
Open AccessBioactive hierarchical silk fibers created by bioinspired self-assembly
Artificial recapitulation of the hierarchy of natural protein fibers is crucial to providing strategies for develo** advanced fibrous materials. However, it is challenging due to the complexity of the natura...
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Article
Author Correction: Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessLOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP
LOX-like 1 (LOXL1) is a lysyl oxidase, and emerging evidence has revealed its effect on malignant cancer progression. However, its role in colorectal cancer (CRC) and the underlying molecular mechanisms have n...
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Article
Open AccessCrack-based and Hair-like Sensors Inspired from Arthropods: A Review
Over a long period of time, arthropods evolve to have two excellent mechanical sensilla of slit sensilla and trichobothria sensilla, which construct a perfect perception system. The former mainly perceives the...
